Gestational exposure to phthalates and gender-related play behaviors in 8-year-old children: an observational study

Table 3 Adjusted Associations of Gestational Urinary Phthalate Metabolite Concentrations with the GIQ

Metabolites	GIQ Total Score (Continuous Distribution)						Low GIQ score (GIQ Dichotomized at the < 25th percentile)^b
	Males			Females			Males			Females
	Estimate	95 % CI	p	Estimate	95 % CI	p	OR	95 % CI	p	OR	95 % CI	p
∑DEHP^a	0.01	−0.03, 0.06	0.52	0.03	−0.02, 0.07	0.21	1.13	0.77–1.68	0.53	0.93	0.68–1.27	0.64
MEHP	0.01	−0.02, 0.04	0.61	0.02	−0.01, 0.06	0.21	1.22	0.86–1.73	0.27	0.96	0.71–1.21	0.57
MEHHP	0.01	−0.02, 0.04	0.55	0.03	−0.01, 0.06	0.21	1.15	0.79–1.68	0.47	0.92	0.69–1.22	0.56
MEOHP	0.01	−0.02, 0.04	0.56	0.03	−0.01, 0.07	0.16	1.16	0.79–1.69	0.46	0.91	0.71–1.30	0.51
MECPP	0.01	−0.02, 0.04	0.44	0.03	−0.02, 0.07	0.28	1.09	0.73–1.62	0.68	0.95	0.69–1.31	0.77
MCPP	0.02	−0.03, 0.07	0.43	0.01	−0.07, 0.08	0.93	1.15	0.66–2.00	0.62	1.08	0.63–1.87	0.78
MBzP	−0.01	−0.04, 0.02	0.59	−0.01	−0.05, 0.03	0.67	0.97	0.65–1.46	0.36	0.93	0.71–1.21	0.8
MiBP	0.01	−0.03, 0.05	0.58	0.01	−0.05, 0.07	0.76	1.25	0.78–1.99	0.36	0.81	0.54–1.22	0.32
MnBP	0.02	−0.03, 0.06	0.53	−0.01	−0.06, 0.05	0.84	1.32	0.76–2.29	0.32	1.17	0.78–1.75	0.46
MEP	−0.01	−0.03, 0.02	0.64	0.01	−0.02, 0.05	0.47	1.18	0.87–1.61	0.29	0.92	0.70–1.12	0.53

All values are based on a log₂-transformed exposure and adjusted for race, mother’s education, and relational frustration score. Metabolite concentrations are the mean of the 16 and 26 week gestational urine samples and corrected for creatinine
^a∑DEHP expressed as MEHP, ng/mL (= molar sum of (MECPP, MEOHP, MEOHP, MEHP) in nmol/L *278/1000)
^bDependent variable is a binary indicator of low GIQ score defined as GIQ score <25th percentile of the GIQ score distribution

ISSN: 1476-069X