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Table 3 Associations between occupational groups and blood pressure in different mtDNA function groupsa

From: Occupational exposure to particles and mitochondrial DNA - relevance for blood pressure

 

mtDNA function group

(D-loop)b

mtDNA function group

(MT-TF) c

Low

High

Low

High

Outcome

N

Beta (95% CI)

p

N

Beta (95% CI)

p

N

Beta (95% CI)

p

N

Beta (95% CI)

p

Systolic blood pressure

100

11.32 (6.61, 15.91)

<0.001

106

3.34 (−1.18, 7.85)

0.15

107

12.31 (7.93, 16.69)

<0.001

108

1.11 (−3.51, 5.73)

0.63

Diastolic blood pressure

100

3.53 (0.18, 6.88)

0.039

106

3.64 (0.28, 7.00)

0.034

107

3.00 (−0.38, 6.38)

0.081

108

2.39 (−0.96, 5.73)

0.16

  1. aThe model included age, BMI, family history of cardiovascular disease, smoking history, and current residence as adjustments
  2. bDerived from unmethylated D-loop and relative mtDNA copy number. Two groups stratified by median
  3. cDerived from unmethylated MT-TF and relative mtDNA copy number. Two groups stratified by median
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Environmental Health

ISSN: 1476-069X