PFASs | Number | Number of cases | Crude OR (95%CI) | Adjusted OR (95%CI) | p for sex-PFASs interaction |
---|---|---|---|---|---|
PFOS | |||||
Continuousa | 687 | 173 | 1.17 (0.85–1.62) | 1.23 (0.85–1.76) | 0.33 |
Q1 (< 1.81)b | 171 | 40 | 1 | 1 | 0.26 |
Q2 (1.81–2.48) | 172 | 42 | 1.06 (0.64–1.74) | 0.93 (0.56–1.58) | |
Q3 (2.48–3.24) | 172 | 41 | 1.03 (0.62–1.69) | 1.00 (0.59–1.70) | |
Q4 (≥ 3.24) | 172 | 50 | 1.34 (0.83–2.18) | 1.31 (0.78–2.20) | |
p for trendc | 0.27 | 0.27 | |||
PFOA | |||||
Continuousa | 687 | 173 | 1.44 (1.02–2.03) | 1.35 (0.93–1.97) | 0.17 |
Q1 (< 4.94)b | 171 | 34 | 1 | 1 | 0.14 |
Q2 (4.94–6.98) | 172 | 46 | 1.47 (0.89–2.44) | 1.48 (0.87–2.52) | |
Q3 (6.98–9.55) | 172 | 39 | 1.18 (0.70–1.98) | 1.16 (0.67–2.00) | |
Q4 (≥ 9.55) | 172 | 54 | 1.84 (1.12–3.02) | 1.74 (1.02–2.95) | |
p for trendc | 0.04 | 0.1 | |||
PFNA | |||||
Continuousa | 687 | 173 | 1.49 (0.95–2.32) | 1.53 (0.94–2.47) | 0.46 |
Q1 (< 0.50)b | 171 | 36 | 1 | 1 | 0.33 |
Q2 (0.50–0.64) | 172 | 44 | 1.29 (0.78–2.13) | 1.15 (0.67–1.97) | |
Q3 (0.64–0.83) | 172 | 44 | 1.29 (0.78–2.13) | 1.20 (0.71–2.05) | |
Q4 (≥ 0.83) | 172 | 49 | 1.49 (0.91–2.45) | 1.47 (0.87–2.50) | |
p for trendc | 0.13 | 0.15 | |||
PFDA | |||||
Continuousa | 687 | 173 | 1.18 (0.93–1.50) | 1.22 (0.94–1.58) | 0.65 |
Q1 (< 0.23)b | 171 | 40 | 1 | 1 | 0.68 |
Q2 (0.23–0.36) | 172 | 36 | 0.87 (0.52–1.44) | 0.94 (0.55–1.60) | |
Q3 (0.36–0.54) | 172 | 45 | 1.16 (0.71–1.90) | 1.15 (0.68–1.95) | |
Q4 (≥ 0.54) | 172 | 52 | 1.42 (0.88–2.30) | 1.58 (0.94–2.65) | |
p for trendc | 0.08 | 0.06 | |||
PFUA | |||||
Continuousa | 687 | 173 | 1.18 (0.86–1.63) | 1.24 (0.88–1.75) | 0.67 |
Q1 (< 0.29)b | 171 | 40 | 1 | 1 | 0.83 |
Q2 (0.29–0.40) | 172 | 40 | 0.99 (0.60–1.64) | 1.01 (0.59–1.71) | |
Q3 (0.40–0.53) | 172 | 44 | 1.13 (0.69–1.84) | 1.13 (0.67–1.90) | |
Q4 (≥ 0.53) | 172 | 49 | 1.31 (0.80–2.12) | 1.36 (0.81–2.28) | |
p for trendc | 0.23 | 0.22 | |||
PFDoA | |||||
Continuousa | 687 | 173 | 0.96 (0.70–1.30) | 1.00 (0.72–1.39) | 0.28 |
Q1 (≤ 0.069)b | 171 | 36 | 1 | 1 | 0.76 |
Q2 (0.069–0.094) | 172 | 54 | 1.72 (1.05–2.80) | 1.83 (1.09–3.08) | |
Q3 (0.094–0.125) | 172 | 42 | 1.21 (0.73–2.01) | 1.37 (0.80–2.34) | |
Q4 (≥ 0.125) | 172 | 41 | 1.17 (0.71–1.95) | 1.18 (0.68–2.04) | |
p for trendc | 0.93 | 0.87 | |||
PFHxS | |||||
Continuousa | 687 | 173 | 1.31 (0.80–2.13) | 1.08 (0.62–1.85) | 0.43 |
Q1 (≤ 0.13)b | 171 | 37 | 1 | 1 | 0.05 |
Q2 (0.13–0.16) | 172 | 43 | 1.21 (0.73–1.99) | 1.25 (0.74–2.12) | |
Q3 (0.16–0.20) | 172 | 46 | 1.32 (0.81–2.17) | 1.15 (0.68–1.94) | |
Q4 (≥ 0.20) | 172 | 47 | 1.36 (0.83–2.23) | 1.14 (0.67–1.94) | |
p for trendc | 0.2 | 0.73 | |||
PFBS | |||||
Continuousa | 687 | 173 | 1.20 (0.87–1.66) | 1.22 (0.87–1.72) | 0.83 |
Q1 (≤ 0.037)b | 170 | 39 | 1 | 1 | 0.33 |
Q2 (0.037–0.047) | 171 | 43 | 1.13 (0.69–1.86) | 1.28 (0.75–2.17) | |
Q3 (0.047–0.062) | 174 | 46 | 1.21 (0.74–1.97) | 1.18 (0.70–2.00) | |
Q4 (≥ 0.062) | 172 | 45 | 1.19 (0.73–1.95) | 1.15 (0.68–1.95) | |
p for trendc | 0.46 | 0.70 |