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Table 5 Summary of changes from baseline in urine values

From: Efficacy of N,N‘bis-(2-mercaptoethyl) isophthalamide on mercury intoxication: a randomized controlled trial

Treatment Visit Median p-value*
Mercury in urine [μg/l]
 NBMI 100 mg Day 15 −6.4 (− 128.6–76.1) .892
Day 45 −1.5 (− 126.5–22.2) .812
 NBMI 300 mg Day 15 −8.2 (− 240.9–0.8) .011
Day 45 −6.0 (− 246.9–6.8) .069
 Placebo Day 15 2.7 (−71.9–45.9)  
Day 45 0.1 (−74.7–49.3)  
Mercury in urine [μg/g creatinine]
 NBMI 100 mg Day 15 8.2 (− 135.9–122.8) .849
Day 45 −13.8 (− 140.2–232.5) .894
 NBMI 300 mg Day 15 −24.6 (− 475.5–79.0) .091
Day 45 −4.0 (− 463.3–1110.1) .722
 Placebo Day 15 1.8 (−407.9–297.1)  
Day 45 −5.9 (− 453.7–1557.8)  
  1. Results give the median values measured at each time point. Change of baseline is the difference of the day 15/day 45 value and baseline value in each individual. The median of calculated differences is shown
  2. *Wilcoxon-Mann-Whitney test for differences in change from baseline between treatment groups and placebo