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Table 2 Adjusteda regression models of associations of maternal 1976 TCDD levels with atopic conditions in children, SWHS, Italy, 1976–2016

From: Prenatal exposure to TCDD and atopic conditions in the Seveso second generation: a prospective cohort study

  Adjusted RR (95% CI)
Outcomes Cases N (%) Total Male Female p-interaction
Eczema
 Diagnosis and symptoms 98 (14.5) 0.93 (0.69, 1.27) 1.01 (0.72, 1.41) 0.86 (0.53, 1.37) 0.54
 Diagnosis only 55 (8.2) 0.63 (0.40, 0.99) 0.64 (0.41, 0.99) 0.62 (0.29, 1.32) 0.96
Asthma
 Diagnosis and symptoms 152 (22.5) 0.93 (0.71, 1.21) 0.90 (0.65, 1.24) 0.97 (0.66, 1.43) 0.72
 Diagnosis only 81 (12.0) 0.93 (0.61, 1.40) 1.04 (0.65, 1.66) 0.77 (0.42, 1.40) 0.38
Hay fever
 Diagnosis and symptoms 243 (36.0) 1.02 (0.86, 1.20) 0.91 (0.73, 1.13) 1.20 (0.95, 1.52) 0.07
 Diagnosis only 130 (19.3) 0.99 (0.76, 1.27) 0.94 (0.67, 1.32) 1.04 (0.73, 1.49) 0.67
  1. aModels adjusted for maternal age at explosion, atopic history, age at pregnancy, BMI closest to birth year, smoking during pregnancy, birth order, child sex, child age, and primary wage earner education