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Table 5 Associations between changes (Δ) in PAH metabolites and post-working relative mtDNAcn / TL among asphalt workers; and ΔmtDNAcn / ΔTL in the repeated-measures analysis

From: Occupational exposure to asphalt mixture during road paving is related to increased mitochondria DNA copy number: a cross-sectional study

Study population

ΔPAH metabolites

Post-working relative mtDNAcn

Post-working relative TL

β (95%CI)

pa

β (95%CI)

pa

All asphalt workers

Δln(1-OH-PYR)

0.035 (−0.028, 0.098)

0.28

0.067 (−0.0038, 0.14)

0.064

(N = 138)

Δln(2-OH-PH)

0.048 (−0.015, 0.11)

0.14

0.075 (0.0046, 0.15)

0.037

  

Δ mtDNAcn

Δ TL

  

β (95%CI)

pb

β (95%CI)

pb

Repeated-measures analysis

Δln(1-OH-PYR)

−0.078 (− 0.14, − 0.016)

0.015

−0.064 (− 0.16, 0.028)

0.17

(N = 31)

Δln(2-OH-PH)

−0.057 (− 0.12, 0.0073)

0.080

− 0.048 (− 0.15, 0.049)

0.32

  1. aP values were derived from general linear model with age, BMI, smoking and snus states, cigarette pack-year, investigation season, and occupational groups as adjustments
  2. bP values were derived from linear mixed model with occupational groups and pre-working mtDNAcn or TL as adjustments