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Table 2 Agreement in exposure status among cells (n = 18,270) by threshold for minimum prevalence defining exposure

From: A hybrid expert approach for retrospective assessment of occupational exposures in a population-based case-control study of cancer

 

Percent concordant

Percent discordant

Concordant exposed occupation-agent combinations

Prevalence threshold (1)

Exposed (%)

Unexposed (%)

Exposed Lung (%) (2)

Exposed PROtEuS (%) (3)

Number of combinations (4)

Kendall correlation in probability (5)

Median difference. in probability (%), PROtEuS-Lung (6)

P > 0%

11.8

76.8

6.0

5.4

2162

0.61

−0.2

P ≥ 5%

8.2

85.5

4.1

2.2

1502

0.55

1.3

P ≥ 10%

6.2

90.2

2.2

1.4

1127

0.52

2.4

P ≥ 25%

3.7

94.2

0.9

1.1

685

0.43

2.9

P ≥ 50%

2.2

96.3

0.6

0.9

403

0.36

2.3

  1. 1. Minimum prevalence (proportion of jobs exposed) in cell to be considered exposed
  2. 2. Proportion of cells with non-null exposure in Lung and null exposure in PROtEuS
  3. 3. Proportion of cells with non-null exposure in PROtEuS and null exposure in Lung
  4. 4. Number of concordant exposed occupation-agent combinations
  5. 5. Kendall correlation in the probability of exposure between concordant exposed cells
  6. 6. Median difference in probability (probability in PROtEuS minus probability in Lung) across concordant exposed cell