6 week cohort | 13-week cohort | |||||
---|---|---|---|---|---|---|
Control | Glyphosate | Roundup | Control | Glyphosate | Roundup | |
Serum Hormones | ||||||
No. of females examined | 8 (8) | 8 (8) | 8 (8) | 10 (10) | 10 (10) | 10 (10) |
TT (ng/ml) | 0.66 ± 0.064 | 0.75 ± 0.12 | 0.68 ± 0.11a | 0.51 ± 0.06 | 0.72 ± 0.10 | 0.72 ± 0.07b * |
fT (pg/ml) | 6.49 ± 1.00c | 6.74 ± 1.89d | 7.70 ± 1.35a | 9.18 ± 2.49 | 12.04 ± 1.25 | 12.52 ± 1.76b |
DHT (pg/ml) | 294.28 ± 50.40 | 328.34 ± 51.93a | 488.94 ± 114.68a | 382.93 ± 52.14 | 460.09 ± 60.06 | 268.84 ± 45.56b |
SHBG (ng/ml) | 864.82 ± 30.24 | 952.75 ± 54.98 | 903.07 ± 29.61 | 968.27 ± 21.39 | 993.44 ± 32.79 | 964.81 ± 27.20 |
E2 (pg/ml)g | 14.95 ± 7.24 | 32.24 ± 8.77 | 66.96 ± 25.17 | 18.08 ± 8.49 | 28.48 ± 13.71 | 43.91 ± 9.92 |
Plasma Hormones | ||||||
No. of females examined | 7 (8) | 7 (8) | 6 (8) | 7(10) | 5(10) | 6(10) |
FSH (ng/ml) g | 3.95 ± 2.50 | 2.67 ± 1.22 | 3.15 ± 1.65 | 1.58 ± 0.51 | 1.73 ± 0.64 | 1.46 ± 0.35 |
LH (ng/ml)g | 5.75 ± 3.04 | 4.86 ± 1.93 | 4.52 ± 3.38 | 1.83 ± 0.25 | 2.35 ± 1.11 | 2.16 ± 1.28 |
PRL (ng/ml)g | 102.34 ± 164.71c | 27.49 ± 30.23 | 46.49 ± 31.03 | – | – | – |
GH (ng/ml) | 12.61 ± 13.30 | 3.85 ± 0.97c | 4.16 ± 2.84 | – | – | – |
TSH (ng/ml) | 2.70 ± 1.13 | 3.02 ± 2.00 | 3.04 ± 1.53 | 1.29 ± 0.69e | 1.93 ± 0.89f | 3.03 ± 2.22e |
ACTH (pg/ml) | 331.60 ± 89.59 | 314.09 ± 170.60 | 354.95 ± 104.96 | – | – | – |
BDNF (pg/ml) | 245.03 ± 155.68 | 483.62 ± 301.02 | 351.33 ± 177.28 | 25,399 ± 155.77e | 377.79 ± 226.30f | 249.39 ± 14,566e |