Fig. 1

Epigenetic candidate genes significantly associated with arsenic exposure. Multivariable linear regression analysis of associations between epigenetic candidate gene expression and U-As levels. a) Categorization of candidate epigenetic genes. Graph shows the total number of candidate genes in each category, and the number in each category associated with U-As levels in the unstratified cohort, male placentas, or female placentas. b) Venn diagram showing the number of candidate epigenetic genes whose expression significantly associated with U-As levels, at a significance level of P < 0.05, in the unstratified cohort, male placentas, and/or female placentas. Analyses were adjusted for maternal age at enrollment