Table 1 Weighted LIFECODES demographic characteristics overall and by preeclampsia status: crude N (weighted %) or weighted median (weighted IQR)
|  | Overall (N = 383) | Preeclamptic (N = 28) | Non-Preeclamptic (N = 355) | P * |
|---|---|---|---|---|
Maternal Age (years) | 32.7 (29.1, 35.7) | 33.0 (29.0, 35.1) | 32.7 (29.1, 35.7) | 0.62 |
Pre-pregnancy BMI (kg/m2)a | 23.9 (21.4, 27.9) | 29.8 (24.5, 36.7) | 23.8 (21.3, 27.4) | < 0.01 |
Maternal Race | ||||
 White | 231 (60.3%) | 21 (75.0%) | 210 (59.2%) | 0.11 |
 African American | 57 (14.9%) | 6 (19.4%) | 51 (14.8%) | |
 Other | 95 (24.8%) | 1 (5.6%) | 94 (26.1%) | |
Maternal Educationa | ||||
  < High School | 53 (13.6%) | 7 (21.5%) | 46 (13.1%) | 0.39 |
 Technical College | 57 (14.9%) | 3 (9.7%) | 54 (15.2%) | |
 Junior College or Some College | 115 (31.3%) | 11 (40.3%) | 104 (30.7%) | |
  > College | 148 (40.3%) | 7 (28.5%) | 141 (41.0%) | |
Maternal Health Insuranceb | ||||
 Private/HMO/Self-Pay | 311 (82.7%) | 25 (90.3%) | 286 (82.2%) | 0.31 |
 Public | 63 (17.3%) | 3 (9.7%) | 60 (17.8%) | |
Maternal Smoking During Pregnancyc | ||||
 No | 353 (93.9%) | 24 (91.7%) | 329 (94.0%) | 0.56 |
 Yes | 25 (6.1%) | 4 (8.3%) | 21 (6.0%) | |
Maternal Alcohol Use During Pregnancyb | ||||
 No | 359 (95.2%) | 28 (100.0%) | 331 (94.9%) |  |
 Yes | 15 (4.8%) | 0 (0.0%) | 15 (5.1%) | |
Parity | ||||
 Nulliparous | 167 (43.8%) | 12 (42.4%) | 155 (43.9%) | 0.88 |
 Parous | 216 (56.2%) | 16 (57.6%) | 200 (56.1%) | |
Previous Preeclampsia Diagnosis | ||||
 No | 370 (97.3%) | 24 (91.7%) | 346 (97.7%) | 0.03 |
 Yes | 13 (2.7%) | 4 (8.3%) | 9 (2.3%) | |
Gestational Diabetes | ||||
 No | 355 (93.4%) | 25 (90.3%) | 330 (93.6%) | 0.52 |
 Yes | 28 (6.6%) | 3 (9.7%) | 25 (6.4%) | |
Use of ART | ||||
 No | 349 (90.8%) | 23 (75.7%) | 326 (91.7%) | 0.02 |
 Yes | 34 (9.2%) | 5 (24.3%) | 29 (8.3%) | |
Chronic Hypertension | ||||
 No | 368 (97.1%) | 22 (87.6%) | 346 (97.7%) | < 0.01 |
 Yes | 15 (2.9%) | 6 (12.5%) | 9 (2.3%) | |
Use of Multivitamins During Pregnancyc | ||||
 No | 106 (27.4%) | 8 (30.6%) | 98 (27.2%) | 0.73 |
 Yes | 272 (72.6%) | 20 (69.4%) | 252 (72.8%) | |
Use of Calcium Supplements During Pregnancyc | ||||
 No | 324 (85.9%) | 20 (72.9%) | 304 (86.7%) | 0.07 |
 Yes | 54 (14.1%) | 8 (27.1%) | 46 (13.3%) | |
Use of Iron Supplement During Pregnancyc | ||||
 No | 336 (88.7%) | 24 (91.7%) | 312 (88.5%) | 0.53 |
 Yes | 42 (11.3%) | 4 (8.3%) | 38 (11.5%) | |
Infant Sex | ||||
 Female | 166 (44.7%) | 17 (77.2%) | 149 (42.8%) | < 0.01 |
 Male | 217 (55.3%) | 11 (22.8%) | 206 (57.2%) | |
Maternal sFlt-1Expressiond (ng/mL) | 5.79 (3.85, 9.12) | 6.30 (4.15, 9.88) | 5.72 (3.83, 9.06) | 0.29 |
Maternal PLGF Expressione (pg/mL) | 448 (284, 645) | 275 (421, 132) | 456 (292, 651) | < 0.01 |
Maternal sFlt-1/PLGF Ratiod | 13.8 (8.27, 22.9) | 23.2 (12.0, 39.9) | 13.3 (8.11, 22.3) | 0.03 |