Association between a urinary biomarker for exposure to PAH and blood level of the acute phase protein serum amyloid A in coke oven workers

Table 2 Levels of biomarkers of exposure and effect

Biomarkers/assay [unit]	Median	Mean ± SD	Range	N (%) above the limit value
1-hydroxypyrene urine concentration (μmol/mol creatinine)^a	4.31	6.81 ± 7.40	0.25–31.4	60 (70)
Anti-B[a]PDE-DNA (adducts/ 10⁸ nucleotides)^b	2.89	4.03 ± 3.65	1.00–27.4	85 (98)
SAA (μg/mL)	3.07	34.18 ± 180.14	0.36–1200
CRP (μg/mL)	0.36	0.95 ± 2.73	0.4–24.3

^aShort- PAH exposure was evaluated by means of the urinary excretion of 1-hydroxypyrene. 1-hydroxypyrene levels were reported previously [43]
^bLong-term PAH exposure was evaluated by means of anti-B[a]PDE-DNA adducts. Positive were workers with detectable adducts (> 1 adducts/10⁸ nucleotides). Anti-B[a]PDE-DNA adduct levels were reported previously [43]

ISSN: 1476-069X