Association between a urinary biomarker for exposure to PAH and blood level of the acute phase protein serum amyloid A in coke oven workers

Table 3 Predictors of SAA levels. Multiple linear regression analysis of influence of PAH exposure evaluated by urinary excretion of 1-hydroxypyrene, anti-B[a]PDE-DNA adduct levels in blood cells, GSTM1, CRP, smoking status and diet habits on serum SAA levels in coke oven workers (n = 87)

	1-hydroxypyrene	anti-B[a]PDE-DNA adducts	GSTM1^a	CRP	Smoking^b	Diet^c
β^d	0.56	−0.39	−1.05	7.08	−1.14	0.43
T^d	2.20	0.86	1.61	14.5	1.88	0.70
p-value^d	0.030	0.391	0.110	< 0.0001	0.063	0.487

^aGSTM1 genotypes was treated as dichotomous variables: GSTM1 = 1 or 0, Active or *0/*0
^bSmoking = 1 or 0, current smokers or non-smokers
^cDiet = 1 or 0, charcoaled meat consumption more or less than once per week, respectively
^dThe F test gave an F of 38.6 and a p value of < 0.0001. β is the slope. T is the test statistics β/standard deviation of β
Bold font highlights statistically significant values

ISSN: 1476-069X