Association between a urinary biomarker for exposure to PAH and blood level of the acute phase protein serum amyloid A in coke oven workers

Table 4 Predictors of CRP levels. Multiple linear regression analysis of influence of PAH exposure evaluated by urinary excretion of 1-hydroxypyrene, anti-B[a]PDE-DNA adduct levels in blood cells, GSTM1, SAA, smoking status and diet habits on serum CRP levels in coke oven workers (n = 87)

	1-hydroxypyrene	anti-B[a]PDE-DNA adducts	GSTM1^a	SAA	Smoking^b	Diet^c
β^d	−0.08	0.01	0.02	0.003	0.14	−0.08
T^d	−2.51	0.26	0.21	12.92	1.83	−0.94
p-value^d	0.014	0.793	0.834	< 0.0001	0.072	0.348

^aGSTM1 genotypes was treated as dichotomous variables: GSTM1 = 1 or 0, Active or *0/*0
^bSmoking = 1 or 0, current smokers or non-smokers
^cDiet = 1 or 0, charcoaled meat consumption more or less than once per week, respectively
^dThe F test gave an F of 30.04 and a p value of < 0.0001. β is the slope. T is the test statistics β/standard deviation of β
Bold font highlights statistically significant values

ISSN: 1476-069X