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Table 3 Results of mediation analysis between O3, persistent asthma and plasma FlOPs levels using the CAUSALMED procedure (n = 204)

From: Does the oxidative stress play a role in the associations between outdoor air pollution and persistent asthma in adults? Findings from the EGEA study

OR

Estimate

95% CI

 Odds Ratio Total Effect

2.16

0.70–11.9

 Odds Ratio Natural Direct Effect

1.68

0.57–7.25

 Odds Ratio Natural Indirect Effect

1.28

1.01–2.29

Decomposition of the total effect

 Four-way

Percent

 Controlled direct

50.3

 Reference interaction

8.6

 Mediated interaction

26.5

 Pure indirect

14.6

  1. Models were adjusted for age, sex and smoking habits. The exposure was O3. The mediators were plasma FlOPs levels. The outcome was persistent asthma