Fig. 2

Gene sets differentially related to arsenic exposure and birth weight in female fetal placenta. Enrichment map of gene sets that are associated with increased arsenic exposure and reduced birth weight in female placenta (with a significance level of FDR < 0.05). Clusters thus represent biological themes that may underlie female fetal growth inhibition by arsenic. Red circles; upregulated gene sets, blue circles; downregulated gene sets, large yellow circles; gene set clusters, green lines indicate overlapping genes between gene sets. Clusters were labeled based on the most common themes of the gene sets they comprise. Singleton gene sets are omitted (see Additional file 10A for a complete list of gene sets)