| Control | Risk Level 1 | Risk Level 2 | GEE analysis coefficient B(SE) | |||||
---|---|---|---|---|---|---|---|---|---|
Model 1 | Model 2 | ||||||||
Variablesa | N | Mean ± SD | N | Mean ± SD | N | Mean ± SD | RL1*Time | RL2*Time | RL1*Time |
FVC (%) 1st | 34 | 104.36 ± 10.86 | 53 | 106.17 ± 13.26 | 46 | 104.54 ± 13.2 | 1.164 (0.071) | 0.468 (0.715) | 0.269 (0.356) |
FVC (%) 2nd | 74 | 110.53 ± 20.59 | 81 | 109.51 ± 14.51 | 68 | 110.02 ± 15.39 | |||
FVC (%) 3rd | 73 | 106.18 ± 14.56 | 74 | 107.66 ± 12.05 | 72 | 104.48 ± 11.86 | |||
FVC (%) 4th | 77 | 108.14 ± 17.74 | 67 | 110.75 ± 14.62 | 64 | 107.49 ± 13.07 | |||
FVC (%) 5th | 65 | 106.06 ± 15.67 | 52 | 112.57 ± 15.93 | 57 | 107.94 ± 13.34 | |||
FEV1.0/FVC (%) 1st | 34 | 79.91 ± 7.24 | 53 | 82.23 ± 5.5 | 46 | 81.32 ± 6.43 | -0.269 (0.328) | -0.084 (0.332) | -0.05 (1.673) |
FEV1.0/FVC (%)2nd | 74 | 81.43 ± 6.54 | 81 | 81.59 ± 4.92 | 68 | 81.47 ± 5.78 | |||
FEV1.0/FVC (%) 3rd | 73 | 80.49 ± 6.1 | 74 | 80.67 ± 5.45 | 72 | 82.02 ± 5.73 | |||
FEV1.0/FVC (%) 4th | 77 | 79.46 ± 6.93 | 67 | 79.47 ± 5.43 | 63 | 78.87 ± 6.07 | |||
FEV1.0/FVC (%) 5th | 65 | 80.34 ± 6.22 | 52 | 78.43 ± 5.56 | 57 | 79.57 ± 6.01 | |||
MMF (%) 1st | 34 | 83.29 ± 27.74 | 53 | 88.53 ± 21.09 | 46 | 84.69 ± 22.79 | 0.737 (1.084) | 0.694 (1.082) | 0.346 (0.542) |
MMF (%) 2nd | 74 | 91.41 ± 25.02 | 81 | 87.84 ± 20.43 | 68 | 91.6 ± 27.21 | |||
MMF (%) 3rd | 73 | 82.13 ± 22.35 | 74 | 83.45 ± 19.68 | 72 | 86.99 ± 21.13 | |||
MMF (%) 4th | 78 | 81.63 ± 20.93 | 67 | 81.69 ± 20.38 | 64 | 79.1 ± 22.4 | |||
MMF (%) 5th | 65 | 81.28 ± 21.85 | 52 | 79.7 ± 21.17 | 57 | 80.38 ± 22.13 | |||
PEFR (%) 1st | 34 | 99.03 ± 19.79 | 53 | 102.48 ± 13.82 | 46 | 99.93 ± 14.53 | 0.663 (0.889) | 0.746 (0.962) | 0.413 (0.480) |
PEFR (%) 2nd | 74 | 101.91 ± 17.9 | 81 | 102.86 ± 18.56 | 68 | 105.52 ± 20.51 | |||
PEFR (%) 3rd | 73 | 98.48 ± 15.69 | 74 | 105.89 ± 14.9 | 72 | 103.23 ± 16.68 | |||
PEFR (%) 4th | 78 | 94.96 ± 17.81 | 67 | 104.76 ± 12.95 | 64 | 99.08 ± 18.79 | |||
PEFR (%) 5th | 65 | 98.62 ± 15.35 | 52 | 104.23 ± 13.73 | 57 | 102 ± 20.13 |