| User groups of skincare products per cancer type | n | Cancer cases | Age-adjusted HR (95% CI) | Multivariable HR (95% CI) | ptrend |
|---|
| Premenopausal breast cancera |
| Non−/Light users | 7988 | 238 | 1.00 | 1.00 | 0.56 |
| Moderate users | 4642 | 146 | 1.05 (0.86,1.30) | 1.05 (0.85,1.29) | |
| Frequent/heavy users | 7215 | 237 | 1.11 (0.93,1.33) | 1.10 (0.92,1.32) | |
| Postmenopausal breast cancerb |
| Non-users | 1549 | 49 | 1.12 (0.84,1.49) | 1.14 (0.85,1.52) | 0.27 |
| Light users | 32,379 | 922 | 1.00 | 1.00 | |
| Moderate users | 22,762 | 656 | 1.00 (0.90, 1.10) | 0.99 (0.89,1.09) | |
| Frequent users | 29,874 | 854 | 0.99 (0.90, 1.09) | 0.97 (0.88,1.07) | |
| Heavy users | 1752 | 45 | 0.89 (0.66, 1.20) | 0.87 (0.65,1.18) | |
| Endometrial cancerc |
| Non−/Light users | 25,774 | 213 | 1.00 | 1.00 | 0.63 |
| Moderate users | 16,556 | 98 | 0.70 (0.55,0.88) | 0.77 (0.61,0.98) | |
| Frequent/heavy users | 23,156 | 163 | 0.83 (0.68,1.02) | 0.97 (0.79,1.20) | |
- HR hazard ratio, CI confidence interval
- aMultivariable adjusted for maternal breast cancer history and alcohol intake
- bMultivariable adjusted for body mass index, use of menopause hormone therapy, age at first birth and parity combined, maternal breast cancer history, physical activity and alcohol intake
- cMultivariable adjusted for body mass index, use of oral contraceptives, use of intrauterine device, smoking and education
