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Table 2 Association between pesticide (ever/never use) and aggressive PCa for those pesticides first reported at the Phase 1 take-home (TH) questionnaire in the Agricultural Health Study (AHS)

From: Pesticide exposure and risk of aggressive prostate cancer among private pesticide applicators

Common namePhase 1 take-home questionnaire only
(n = 20,923)
Phase 1 take-home questionnaire including follow-up (Phase 2/Phase 3 questionnaire) exposure informationb
Non-caseAggressive PCaHRa (95% CI)Non-caseAggressive PCaHRa (95% CI)
Herbicide
 Acifluorfen
  Never use16,626744113,3716211
  Ever use34141391.08 (0.90, 1.30)36421461.06 (0.89, 1.27)
 Bromoxynil
  Never use14,609628111,5575231
  Ever use54312551.17 (0.99, 1.37)57582661.14 (0.96, 1.34)
 Clomazone
  Never use16,850756113,4716321
  Ever use31901270.96 (0.79, 1.17)34621320.94 (0.78, 1.14)
 Fluazifop-butyl
  Never use16,682750113,0776201
  Ever use33581331.07 (0.89, 1.29)39091491.01 (0.84, 1.21)
 Imazaquin
  Never use17,052770113,8806461
  Ever use29881130.99 (0.81, 1.20)31011160.99 (0.81, 1.20)
 Linuron
  Never use17,509742114,2676221
  Ever use25311411.19 (0.99, 1.42)25481431.19 (0.996, 1.43)
 Sethoxydim
  Never use14,404647111,4865461
  Ever use56362361.12 (0.96, 1.30)58352391.07 (0.91, 1.24)
 Simazine
  Never use18,454803114,9226711
  Ever use1586801.19 (0.94, 1.51)1724861.17 (0.93, 1.48)
 Sodium bentazon
  Never use12,911573110,2504761
  Ever use71293101.08 (0.93, 1.25)73323171.06 (0.91, 1.23)
 Thifensulfuron-methyl
  Never use18,108821114,3556681
  Ever use1932620.91 (0.70, 1.18)2389831.00 (0.79, 1.26)
Insecticide
 Acephate
  Never use18,069811114,3776711
  Ever use1971721.06 (0.82, 1.39)2427851.00 (0.77, 1.29)
 Bacillus thuringiensis
  Never use18,256813114,8556891
  Ever use1784701.00 (0.77, 1.29)1904710.93 (0.72, 1.20)
 Chloropicrin
  Never use19,644865115,9447301
  Ever use396181.48 (0.92, 2.38)566201.21 (0.77, 1.91)
 Disulfoton
  Never use18,332815114,9276841
  Ever use1708680.96 (0.74, 1.26)1807720.96 (0.74, 1.25)
 Dimethoate
  Never use19,262829115,6736951
  Ever use778541.37 (1.04, 1.80)870551.29 (0.98, 1.70)
 Endosulfan
  Never use19,407860115,7777221
  Ever use633230.85 (0.56, 1.30)750250.78 (0.51, 1.17)
 Methomyl
  Never use18,532827115,1336981
  Ever use1508561.05 (0.78, 1.40)1597581.03 (0.77, 1.37)
 Tefluthrin
  Never use18,635828114,8056841
  Ever use1405550.99 (0.75, 1.31)1855710.98 (0.76, 1.25)
Nematicide
 1, 3-dichloropropene
  Never use19,172848115,6697161
  Ever use868351.14 (0.80, 1.62)944371.11 (0.78, 1.57)
Other
 Arsenical pesticidesc
  Never use19,3098281
  Ever use731551.17 (0.88, 1.55)
  1. aUsing age as the time metric and adjusted for state, birth year, family history of PCa, race, and smoking status
  2. bNumbers add to less than total number of take-home responders (n = 20,923) due to missing responses for follow-up use information
  3. cArsenical pesticides consist of lead arsenate (insecticide), organic arsenic (herbicide), and inorganic arsenic (herbicide); only reported use reported on take-home questionnaire