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Table 1 Clinical characteristics of asthma patients at stable disease and during loss of control

From: Ex vivo innate responses to particulate matter from livestock farms in asthma patients and healthy individuals

 

Stable

Loss of control

P-value

ACQ

6.30 ± 1.04

20.60 ± 0.88

< 0.0001

WURSS

41.10 ± 8.97

60.10 ± 10.48

0.04

FEV1% predicted

103.0 ± 3.70

90.30 ± 5.89

0.01

FeNO (ppb)

39.40 ± 13.33

61.70 ± 15.40

0.24

Sputum eosinophils (%)

2.58 ± 1.45

13.46 ± 4.62

0.03

Sputum neutrophils (%)

41.90 ± 12.20

44.56 ± 8.30

0.65

Blood eosinophils (%)

3.39 ± 0.85

6.33 ± 2.15

0.07

Blood eosinophils (109/L)

0.22 ± 0.06

0.43 ± 0.17

0.13

Blood neutrophils (%)

55.19 ± 3.58

52.86 ± 3.23

0.19

Blood neutrophils (109/L)

3.80 ± 0.72

3.34 ± 0.32

0.35

  1. Data (mean ± SEM) for the 10 asthma patients of whom PBMCs were used. Data for all patients included in the corticosteroid interruption study is provided elsewhere [9,10,11]. ACQ, Asthma Control Questionnaire; WURSS, Wisconsin Upper Respiratory Symptom Survey; FEV1, forced expiratory volume in 1 second; FeNO, fraction exhaled nitric oxide
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Environmental Health

ISSN: 1476-069X