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Table 3 Association between PFAS and risk of hypertension from GAM models adjusted by several covariates, using PFAS quartiles (n = 15,786): odds ratios (OR) and 95% Confidence Intervals (CI)

From: Perfluoroalkyl substances are associated with elevated blood pressure and hypertension in highly exposed young adults

PFAS Total Males Females
OR CI Lower CI Upper OR CI Lower CI Upper OR CI Lower CI Upper
ln_PFOA 1.06 1.01 1.12 1.08 1.02 1.15 1.06 0.97 1.15
IQ 1    1    1   
II Q 1.00 0.85 1.16 1.00 0.81 1.24 1.05 0.84 1.32
III Q 1.02 0.87 1.20 1.11 0.90 1.36 0.93 0.71 1.23
IV Q 1.16 0.99 1.37 1.21 0.99 1.48 1.17 0.84 1.62
ln_PFOS 1.12 1.02 1.22 1.17 1.05 1.31 1.06 0.91 1.24
IQ 1    1    1   
II Q 0.99 0.85 1.16 1.10 0.88 1.37 0.97 0.77 1.22
III Q 1.06 0.91 1.24 1.26 1.02 1.55 0.85 0.65 1.12
IV Q 1.12 0.95 1.32 1.28 1.03 1.58 1.02 0.74 1.41
ln_PFHxS 1.08 1.02 1.15 1.11 1.03 1.19 1.08 0.97 1.20
IQ 1    1    1   
II Q 1.01 0.86 1.19 1.08 0.85 1.37 1.01 0.80 1.26
III Q 1.08 0.92 1.27 1.19 0.95 1.50 1.00 0.77 1.30
IV Q 1.19 1.00 1.41 1.27 1.02 1.59 1.28 0.90 1.83
ln_PFNA 1.10 0.96 1.26 1.19 1.02 1.40 0.94 0.71 1.25