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Table 3 Association between PFAS and risk of hypertension from GAM models adjusted by several covariates, using PFAS quartiles (n = 15,786): odds ratios (OR) and 95% Confidence Intervals (CI)

From: Perfluoroalkyl substances are associated with elevated blood pressure and hypertension in highly exposed young adults

PFAS

Total

Males

Females

OR

CI Lower

CI Upper

OR

CI Lower

CI Upper

OR

CI Lower

CI Upper

ln_PFOA

1.06

1.01

1.12

1.08

1.02

1.15

1.06

0.97

1.15

IQ

1

  

1

  

1

  

II Q

1.00

0.85

1.16

1.00

0.81

1.24

1.05

0.84

1.32

III Q

1.02

0.87

1.20

1.11

0.90

1.36

0.93

0.71

1.23

IV Q

1.16

0.99

1.37

1.21

0.99

1.48

1.17

0.84

1.62

ln_PFOS

1.12

1.02

1.22

1.17

1.05

1.31

1.06

0.91

1.24

IQ

1

  

1

  

1

  

II Q

0.99

0.85

1.16

1.10

0.88

1.37

0.97

0.77

1.22

III Q

1.06

0.91

1.24

1.26

1.02

1.55

0.85

0.65

1.12

IV Q

1.12

0.95

1.32

1.28

1.03

1.58

1.02

0.74

1.41

ln_PFHxS

1.08

1.02

1.15

1.11

1.03

1.19

1.08

0.97

1.20

IQ

1

  

1

  

1

  

II Q

1.01

0.86

1.19

1.08

0.85

1.37

1.01

0.80

1.26

III Q

1.08

0.92

1.27

1.19

0.95

1.50

1.00

0.77

1.30

IV Q

1.19

1.00

1.41

1.27

1.02

1.59

1.28

0.90

1.83

ln_PFNA

1.10

0.96

1.26

1.19

1.02

1.40

0.94

0.71

1.25

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Environmental Health

ISSN: 1476-069X