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Table 2 Riska of incident diabetes for those with above median values of aryl hydrocarbon receptor ligand-mediated luciferase bioactivity (AhRL) and intracellular ATP content (MIS-ATP) in serum incubated samples

From: Aryl-hydrocarbon receptor binding and the incidence of type 2 diabetes: the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

 

Crude

Adjusted

HR (95%CI)

HR (95%CI)

AhRL (FI)

  < 2.04

1

1

  > 2.04

1.85 (1.11; 3.06)

1.69 (1.01; 2.83)

MIS-ATP (%)

  > 87.64

1

1

  < 87.64

3.62 (2.06; 6.38)

3.26 (1.84; 5.78)

  1. aAs determined through proportional hazards modeling for incident analyses, adjusted utilizing a propensity score based on age, sex, family history of diabetes, hypertension, educational attainment, self-reported ethnicity, smoking status, BMI and waist/hip ratio. FI = fold induction; % = % of ATP content present in control cells incubated with charcoal stripped serum