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Table 4 Associations between source-specific PM10 exposure in different pregnancy periods and adverse birth outcomes (Multiple imputation, fully adjusted Model)

From: Trimester effects of source-specific PM10 on birth weight outcomes in the Avon Longitudinal Study of Parents and Children (ALSPAC)

Per IQR increase

Mean difference

Odd ratios

Birth weight, grams

HC, cm

BL, cm

PTBa (case: 601)

TLBWb (case: 271)

SGAc (case: 928)

in exposure

(N = 11,896)

(N = 9245)

(N = 7583)

(N = 12,020)

(N = 11,302)

(N = 11,896)

PM10_road (μg/m3)

 First trimester

−4.25(−14.06, 5.55)

0.00 (−0.03, 0.03)

0.03 (−0.02, 0.08)

1.00 (0.92, 1.09)

1.18 (1.05, 1.32)

1.03 (0.97, 1.10)

 Second trimester

−7.51(−17.02, 1.99)

−0.02 (−0.05, 0.01)

0.01 (−0.04, 0.05)

1.01 (0.93, 1.10)

1.17 (1.06, 1.31)

1.04 (0.98, 1.11)

 Third trimester

−7.89 (−17.54, 1.75)

−0.01 (−0.04, 0.02)

0.02 (−0.03, 0.07)

1.01 (0.93,1.09)

1.17 (1.05,1.31)

1.05 (0.98,1.12)

 Total pregnancy

−7.48(−17.48, 2.52)

−0.01 (−0.04, 0.02)

0.02 (−0.03, 0.07)

1.01 (0.93, 1.10)

1.19 (1.06, 1.33)

1.04 (0.98, 1.12)

PM10_other (μg/m3)

 First trimester

−3.76 (−15.46, 7.92)

0.03 (−0.01, 0.07)

0.07 (0.01, 0.13)

1.01 (0.92, 1.12)

1.15 (0.98, 1.34)

1.05 (0.97, 1.14)

 Second trimester

−4.56 (−16.44, −7.31)

−0.02 (−0.06, 0.02)

0.01 (−0.04, 0.07)

1.03 (0.93,1.14)

1.19 (1.02, 1.39)

1.08 (1.00, 1.18)

 Third trimester

−3.80 (−15.58, 7.99)

0.01 (−0.03, 0.04)

0.03 (−0.03, 0.09)

1.04 (0.94,1.15)

1.23 (1.05, 1.44)

1.14 (1.05, 1.24)

 Total pregnancy

−8.02 (−20.03, 4.00)

0.01 (−0.03, 0.04)

0.04 (−0.02, 0.10)

1.04 (0.94, 1.15)

1.20 (1.03, 1.41)

1.10 (1.01, 1.19)

PM10_total (μg/m3)

 First trimester

2.73 (−11.41, 16.87)

0.09 (0.05, 0.14)

0.16 (0.09, 0.23)

0.98 (0.87,1.11)

0.98 (0.80, 1.20)

0.94 (0.85, 1.04)

 Second trimester

−7.03 (−21.23, 7.17)

−0.06 (−0.10, −0.01)

0.00 (−0.07, 0.08)

0.96 (0.85,1.09)

1.12 (0.92,1.36)

1.02 (0.92, 1.13)

 Third trimester

−7.81 (−19.9, 4.29)

0.00 (−0.03, 0.04)

0.02 (−0.03, 0.08)

1.06 (0.96, 1.18)

1.24 (1.05, 1.47)

1.15 (1.06, 1.25)

 Total pregnancy

−16.05 (−28.21, −3.88)

0.01 (−0.03,0.05)

0.09 (0.03, 0.15)

1.10 (0.99, 1.22)

1.19 (1.00, 1.42)

1.07 (0.98,1.17)

  1. Model adjusted for infant’s sex, maternal age, pre-pregnancy maternal body mass index (BMI), maternal educational level, maternal smoking during first 3 months of pregnancy, and environmental tobacco smoke exposure during pregnancy.
  2. arepresents the increase in odds of PTB for a per IQR increase in PM10 exposure;
  3. brepresents the increase in odds of TLBW for a per IQR increase in PM10 exposure;
  4. crepresents the increase in odds of SGA for a per IQR increase in PM10 exposure
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Environmental Health

ISSN: 1476-069X