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Table 4 Summary of results of meta-analyses. Number of differentially methylated probes (DMPs) and differentially variable probes (DVPs) and values of the genomic inflation factor (λ) in the PBMC meta-analysis (i.e., including the Chile PBMC study, Bangladesh 450 K study, and Bangladesh 850 K study) and PBMC + buccal cell meta-analysis (i.e., including the Chile buccal cell study)

From: Exposure to arsenic at different life-stages and DNA methylation meta-analysis in buccal cells and leukocytes

 

Adjusted for sex, age, and smoking status

Adjusted for cell type proportions, age, and smoking status

 

p < 0.05

FDR < 0.05

λ

p < 0.05

FDR < 0.05

λ

DMPs

 PBMCs

19,632

0

0.98

23,361

1

1.07

 PBMCs + buccal cells

21,321

0

1.04

22,612

3

1.06

DVPs

 PBMCs

26,431

25

1.13

28,578

23

1.17

 PBMCs + buccal cells

24,912

20

1.11

28,399

19

1.18

  1. DMP differentially methylated position, DVP differentially variable position