| |
Total
|
Controls A + B
|
All TGCT cases
|
Non-Seminomas
|
Seminomas
|
P-HETb
|
|---|
|
(N = 578)
|
(N = 274)
|
(N = 304)
|
(N = 132)
|
(N = 144)
|
|---|
|
n (%)
|
n (%)
|
n (%)
|
ORa (95% CI)
|
n (%)
|
ORa (95% CI)
|
n (%)
|
ORa (95% CI)
|
|---|
|
Domestic use of insecticides
| | | | | | | | |
0.12
|
|
No
|
129 (22.3)
|
62 (22.6)
|
67 (22)
|
1.00
|
28 (21.2)
|
1.00
|
34 (23.6)
|
1.00
| |
|
Yes
|
447 (77.3)
|
211 (77.0)
|
236 (77.6)
|
1.27 (0.80, 2.01)
|
104 (78.8)
|
1.78 (0.91, 3.48)
|
109 (75.7)
|
0.89 (0.50, 1.59)
| |
|
Missing
|
2 (0.3)
|
1 (0.4)
|
1 (0.3)
|
–
|
0 (0.0)
|
–
|
1 (0.7)
|
–
| |
|
Domestic use of fungicides
| | | | | | | | |
0.08
|
|
No
|
478 (82.7)
|
234 (85.4)
|
244 (80.3)
|
1.00
|
100 (75.8)
|
1.00
|
123 (85.4)
|
1.00
| |
|
Yes
|
92 (15.9)
|
37 (13.5)
|
55 (18.1)
|
1.73 (1.04, 2.87)
|
31 (23.5)
|
2.44 (1.26, 4.74)
|
18 (12.5)
|
1.04 (0.52, 2.07)
| |
|
Missing
|
8 (1.4)
|
3 (1.1)
|
5 (1.6)
|
–
|
1 (0.8)
|
–
|
3 (2.1)
|
–
| |
|
Domestic use of herbicides
| | | | | | | | |
0.17
|
|
No
|
508 (87.9)
|
242 (88.3)
|
266 (87.5)
|
1.00
|
111 (84.1)
|
1.00
|
129 (89.6)
|
1.00
| |
|
Yes
|
70 (12.1)
|
32 (11.7)
|
38 (12.5)
|
1.15 (0.67, 2.00)
|
21 (15.9)
|
1.64 (0.83, 3.27)
|
15 (10.4)
|
0.80 (0.37, 1.71)
| |
|
Missing
|
0 (0.0)
|
0 (0)
|
0 (0.0)
|
–
|
0 (0.0)
|
–
|
0 (0.0)
|
–
| |
|
Domestic use of any pesticides
| | | | | | | | |
0.18
|
|
No
|
119 (20.6)
|
57 (20.8)
|
62 (20.4)
|
1.00
|
25 (18.9)
|
1.00
|
32 (22.2)
|
1.00
| |
|
Yes
|
456 (78.9)
|
215 (78.5)
|
241 (79.3)
|
1.18 (0.74, 1.88)
|
107 (81.1)
|
1.56 (0.79, 3.06)
|
111 (77.1)
|
0.84 (0.47, 1.51)
| |
|
Missing
|
3 (0.5)
|
2 (0.7
|
1 (0.3)
|
–
|
0 (0.0)
|
–
|
1 (0.7)
|
–
| |
- OR odds ratios, CI confidence intervals
- a Estimates obtained comparing TGCT cases to group A and group B controls combined. Analysis was restricted to subjects with no missing data for the exposure variable (0.2 to 1.4% excluded)
- b P-value for heterogeneity derived from the Likelihood Ratio Test, comparing seminoma versus non-seminoma tumours
