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Table 3 Association of prenatal ambient air pollutants with maternal depression at 12 months postpartum

From: Prenatal ambient air pollution and maternal depression at 12 months postpartum in the MADRES pregnancy cohort

Pollutant

Exposure Averaging Period

Model 1: Unadjusted

Model 2: Adjustedb

Model 3: Adjustedb with Firth’s Correction

N

ORa (95% CI)

N

OR (95% CI)

N

OR (95% CI)

NO2(ppb)

Trimester 1

179

1.02 (0.68, 1.53)

179

1.29 (0.70, 2.40)

179

1.24 (0.72, 2.14)

Trimester 2

180

1.82 (1.22, 2.73)**

180

2.63 (1.41, 4.89)**

180

2.22 (1.28, 3.85)**

Trimester 3

179

1.03 (0.69, 1.53)

179

0.91 (0.55, 1.49)

179

0.92 (0.59, 1.44)

Across Pregnancy

180

1.58 (1.05, 2.37)*

180

2.04 (1.13, 3.69)*

180

1.82 (1.08, 3.07)*

O3(ppb)

Trimester 1

179

0.89 (0.60, 1.33)

179

0.60 (0.31, 1.16)

179

0.65 (0.37, 1.16)

Trimester 2

180

0.75 (0.51, 1.12)

180

0.68 (0.35, 1.32)

180

0.73 (0.40, 1.31)

Trimester 3

179

1.14 (0.76, 1.70)

179

1.48 (0.84, 2.63)

179

1.40 (0.84, 2.35)

Across Pregnancy

180

0.87 (0.57, 1.32)

180

0.88 (0.53, 1.47)

180

0.90 (0.57, 1.45)

PM2.5(μg/m3)

Trimester 1

180

0.79 (0.52, 1.20)

180

0.80 (0.47, 1.35)

180

0.86 (0.54, 1.36)

Trimester 2

180

1.40 (0.95, 2.06)

180

1.56 (1.01, 2.42)*

180

1.47 (0.98, 2.19)

Trimester 3

179

0.94 (0.63, 1.41)

179

0.93 (0.57, 1.51)

179

0.95 (0.61, 1.47)

Across Pregnancy

180

1.11 (0.75, 1.64)

180

1.33 (0.83, 2.15)

180

1.28 (0.82, 1.99)

PM10(μg/m3)

Trimester 1

179

0.88 (0.59, 1.31)

179

0.69 (0.37, 1.28)

179

0.76 (0.44, 1.30)

Trimester 2

180

1.34 (0.92, 1.97)

180

1.58 (0.97, 2.56)

180

1.46 (0.94, 2.28)

Trimester 3

179

1.03 (0.69, 1.53)

179

1.02 (0.58, 1.80)

179

1.02 (0.61, 1.70)

Across Pregnancy

180

1.17 (0.79, 1.73)

180

1.27 (0.80, 2.04)

180

1.22 (0.79, 1.88)

  1. *p < 0.05; **p < 0.01
  2. aAll odds ratios (OR) are scaled to one SD in exposure over the averaging period for each pollutant
  3. bAdjusted for recruitment site, maternal age, ethnicity by nativity, household income, education, air conditioning use during pregnancy, previous history of depression, and average temperature over the exposure averaging period