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Table 1 Distribution of baseline characteristics by exposure status among CCHSa Phase II analysis population, 2017–2020

From: Prenatal and early childhood exposure to tetrachloroethylene (PCE)-contaminated drinking water and sleep quality in adulthood: a retrospective cohort study

 

Prenatal and Early Childhood PCE Exposure Statusb

 

Unexposed

Exposed

Characteristic

N = 248

N = 356

Demographics

 Current Age, mean ± SD

40.7 ± 3.8

40.3 ± 3.7

Year of birth, n (%)

 1969–1974

64 (25.8%)

76 (21.4%)

 1975–1980

130 (52.4%)

186 (52.3%)

 1981–1983

54 (21.8%)

94 (26.4%)

Race, n (%)

 White

246 (99.2%)

352 (98.9%)

 Non-white

2 (0.8%)

4 (1.1%)

Sex at birth, n (%)

 Female

173 (69.8%)

224 (62.9%)

 Male

75 (30.2%)

132 (37.1%)

Educational level, n (%)

 High school graduate or less

15 (6.1%)

18 (5.1%)

 Some college or 2-year degree

45 (18.2%)

61 (17.2%)

 4-year college grad or higher

187 (75.7%)

276 (77.8%)

 Missing

1

1

Currently employed, n (%)

 Yes

219 (90.1%)

320 (90.4%)

 No

24 (9.9%)

34 (9.6%)

 Missing

5

2

Current marital status, n (%)

 Married or cohabitating

197 (79.4%)

308 (86.5%)

 Separated

3 (1.2%)

1 (0.3%)

 Divorced

21 (8.5%)

16 (4.5%)

 Widowed

0 (0.0%)

1 (0.3%)

 Never Married

27 (10.9%)

30 (8.4%)

Behavioral and Health History

 Ever had solvent-exposed job, n (%)

  

 Yes

34 (14.1%)

54 (15.6%)

 No

208 (86.0%)

292 (84.4%)

 Missing

6

10

Ever had solvent-exposed hobby, n (%)

 Yes

216 (87.8%)

299 (84.7%)

 No

30 (12.2%)

54 (15.3%)

 Missing

2

3

History of learning problem, n (%)

 Yes

43 (17.5%)

64 (18.3%)

 No

203 (82.5%)

286 (81.7%)

 Missing

2

6

Ever repeated grade, n (%)

 Yes

27 (10.9%)

33 (9.4%)

 No

220 (89.1%)

318 (90.6%)

 Missing

1

5

History of military service, n (%)

 Yes

16 (6.5%)

20 (5.6%)

 No

232 (93.6%)

336 (94.4%)

History of mental disorder, n (%)

 Yes

91 (36.8%)

146 (41.4%)

 No

156 (63.2%)

207 (58.6%)

 Missing

1

3

Family Characteristics

 Mother’s age at subject’s birth (years), mean ± SD

27.7 ± 4.4

27.5 ± 4.5

 Father’s age at subject’s birth (years), mean ± SD

30.0 ± 5.3

29.9 ± 5.5

Mother’s educational level at subject’s birth, n (%)

 High school graduate or less

69 (27.9%)

119 (33.4%)

 Some college

88 (35.6%)

101 (28.4%)

 4-year college graduate or higher

90 (36.4%)

136 (38.2%)

 Missing

1

0

Mother’s occupational exposure to solvents, n (%)

 Yes

26 (13.1%)

45 (15.0%)

 No

173 (86.9%)

256 (85.1%)

 Missing

49

55

Father’s occupation at subject’s birth, n (%)

 White collar

121 (49.2%)

204 (57.8%)

 Blue collar

76 (30.9%)

105 (29.8%)

 Other

49 (19.9%)

44 (12.5%)

 Missing

2

3

Number of older siblings, n (%)

 0

116 (47.2%)

167 (46.9%)

 1

78 (31.7%)

124 (34.8%)

 2+

52 (21.1%)

65 (18.3%)

 Missing

2

0

Family history of alcohol problem, n (%)

 Yes

103 (41.7%)

170 (47.8%)

 No

136 (55.1%)

177 (49.7%)

 Don’t know

8 (3.2%)

9 (2.5%)

 Missing

1

0

Family history of drug problem, n (%)

 Yes

54 (21.8%)

80 (22.5%)

 No

181 (73.0%)

257 (72.2%)

 Don’t know

13 (5.2%)

19 (5.3%)

Perinatal Characteristics

Subject’s birth weight (g), mean ± SD

3398.8 ± 556.4

3425.9 ± 506.9

Subject’s gestational age (months), mean ± SD

39.9 ± 2.2

40.1 ± 2.6

Mother received prenatal care during subject’s gestation, n (%)

 Yes

236 (100.0%)

345 (99.7%)

 No

0 (0.0%)

1 (0.3%)

 Missing

12

10

Mother’s cigarette smoking during subject’s gestation, n (%)

 Didn’t smoke

158 (77.8%)

233 (76.6%)

 1–10 cigarettes/day

22 (10.8%)

32 (10.5%)

 11+ cigarettes/day

23 (11.3%)

39 (12.8%)

 Missing

45

52

Mother’s alcohol consumption during subject’s gestation, n (%)

 Didn’t drink

115 (56.7%)

155 (51.2%)

 1–3 drinks/month

60 (29.6%)

85 (28.1%)

 1+ drinks/week

28 (13.8%)

63 (20.8%)

 Missing

45

53

Mother’s use of marijuana during subject’s gestation, n (%)

 Yes

9 (4.5%)

10 (3.3%)

 No

192 (95.5%)

295 (96.7%)

 Missing

47

51

Mother’s medical and obstetrical complications during subject’s gestation, n (%)

 Yes

50 (25.0%)

59 (19.5%)

 No

150 (75.0%)

243 (80.5%)

 Missing

48

54

Multiple pregnancy, n (%)

 Yes

10 (4.0%)

8 (2.3%)

 No

238 (96.0%)

348 (97.8%)

Subject breast fed, n (%)

 Yes

137 (68.5%)

198 (65.6%)

 No

63 (31.5%)

104 (34.4%)

 Missing

48

54

  1. a Cape Cod Health Study
  2. b Participants are considered exposed if they have any pre- or postnatal PCE exposure, and unexposed if they have no exposure
  3. c All percentages are presented as proportions of non-missing information