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Table 7 Doses of Yellow No. 5 that elicited effects in children’s clinical trials

From: Potential impacts of synthetic food dyes on activity and attention in children: a review of the human and animal evidence

Study

Rowe and Rowe (1994)

Rowe (1988)

Levy et al. 1978

Levy and Hobbs (1978)

Administered amount

0, 1, 2, 5, 10, or 20 mg

50 mg

5 mg

4 mg

Estimated effective dose (mg/kg/day)

0.04a

0.9–2.7b

0.2–0.3 b

0.1–0.2 b

  1. a LOAEL dose estimated for the mean age of 7 years
  2. b single dose studies, dose estimated for reported range of ages of children
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Environmental Health

ISSN: 1476-069X