Table 4 PCE risk-specific dose calculations using WHO/IPCS 2017 workflow. The POD is 3.6 ppm (Echeverria et al., 1995)

Point of Departure

3.6 ppm

1.89^a

Human Variability^b

I=1%: 9.7

I=0.1%: 20.42

I=1%: 4.3

I=0.1%: 6.99

HD_.05^1% (I=1%)^c

3.6/(9.7) = 0.37 ppm

10^{[(log1.89)2 + (log4.3)2]1/2}= 4.88

HD_.05^1% (I=1%)^c

(1-in-100, 95% conf)

HD_.05^0.1% (I=0.1%)^c

3.6/(20.42)= 0.18 ppm

10^{[(log1.89)2 + (log6.99)2]1/2}= 7.70

HD_.05^0.1% (I-0.1%)^c

(1-in-1000, 95% conf)