Table 7 Ratings for the certainty of the evidence
| Â | Boys | Girls | ||||||
|---|---|---|---|---|---|---|---|---|
Outcomes | Prenatal General | Prenatal Nonverbal | Prenatal Verbal | Postnatal Lead | Prenatal General | Prenatal Nonverbal | Prenatal Verbal | Postnatal Lead |
Initial Rate of Confidence | Moderate | Moderate | Moderate | Moderate | Moderate | Moderate | Moderate | Moderate |
Downgrading Factors | ||||||||
 Risk of Bias | 0 | 0 | -1 | -2 | 0 | 0 | 0 | -2 |
 Inconsistency | 0 | 0 | 0 | -1 | -1 | 0 | 0 | -1 |
 Indirectness | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
 Imprecision | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
 Publication Bias | -1 | -1 | -2 | -1 | -1 | -1 | -2 | -2 |
Upgrading Factors | ||||||||
 Large Magnitude | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
 Dose Response | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
 Residual Confounding | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Overall | ||||||||
 Quality | Moderate | Moderate | Low | Low | Low | Moderate | Moderate | Low |
 Strength | Limited Evidence of Toxicity | Limited Evidence of Toxicity | Inadequate Evidence of Toxicity | Inadequate Evidence of Toxicity | Inadequate Evidence of Toxicity | Insufficient Evidence of toxicity | Inadequate Evidence of Toxicity | Inadequate Evidence of Toxicity |