Fig. 2
The joint association of the included air pollutant exposure and genetic categories with the risk of incident CAD in the UK Biobank. A Joint effects of PM2.5 and genetic variations; (B) Joint effects of PM10 and genetic variations; (C) Joint effects of NO2 and genetic variations; (D) Joint effects of NOx and genetic variations. Adjusted for age (continuous), sex (male/female), alcohol consumption (never, previous, current, missing), smoking status (never, previous, current, missing), body mass index (< 25 kg/m2, 25 to 29.9 kg/m2, ≥ 30 kg/m2, missing), education level (College or University degree, A/AS-level, O-level/GCSE, CSE, NVQ/HND/HNC, other qualifications, none), UK Biobank assessment center, physical activity (continuous, MET-min/week), diabetes at baseline (yes/no), cardiovascular disease at baseline (yes/no), genotyping batch, and the first 4 genetic principal components