Table 1 Baseline characteristics of participants in the UK Biobank study
Characteristic | Incident coronary artery disease | |||||
|---|---|---|---|---|---|---|
PM dataset (n = 447,530) | NO dataset (n = 480,298) | |||||
Yes (n = 22,897) | No (n = 464,610) | P | Yes (n = 22,897) | No (n = 464,610) | P | |
Age (years, mean ± SD) | 61.0 ± 6.5 | 56.2 ± 8.1 |  < 0.001 | 61.0 ± 6.5 | 56.1 ± 8.1 |  < 0.001 |
Male (%) | 14,122 (66.7) | 186,112 (43.7) |  < 0.001 | 15,109 (66.8) | 199,348 (43.6) |  < 0.001 |
White (%) | 19,741 (93.4) | 399,740 (93.9) |  < 0.001 | 21,118 (93.6) | 430,436 (94.2) |  < 0.001 |
BMI (kg/m2, mean ± SD) | 29.0 ± 5.0 | 27.3 ± 4.8 |  < 0.001 | 29.0 ± 5.0 | 27.3 ± 4.8 |  < 0.001 |
BMI (kg/m2, %) |  |  |  < 0.001 |  |  |  < 0.001 |
 Normal (< 25 kg/m2) | 4,357 (20.6) | 144,450 (33.9) |  | 4,607 (20.4) | 155,268 (33.9) |  |
 Overweight (25 to 29.9 kg/m2) | 9,183 (43.3) | 179,600 (42.1) |  | 9,852 (43.6) | 192,827 (42.1) |  |
 Obesity (≥ 30 kg/m2) | 7,443 (35.1) | 99,791 (23.4) |  | 7,924 (35.0) | 106,987 (23.4) |  |
 Missing value | 206 (1.0) | 2,500 (0.6) |  | 225 (1.0) | 2,608 (0.6) |  |
 Physical activity (MET, min/week, mean ± SD) | 2634.0 ± 2503.0 | 2664.8 ± 2431.7 | 0.072 | 2625.2 ± 2497.3 | 2656.4 ± 2424.2 | 0.059 |
Education level |  |  |  < 0.001 |  |  |  < 0.001 |
 College or University degree | 4,758 (22.8) | 137,556 (32.6) |  | 5,149 (23.1) | 150,059 (33.1) |  |
 A/AS-level | 1,732 (8.3) | 47,642 (11.3) |  | 1,863 (8.4) | 51,397 (11.3) |  |
 O-level/GCSE | 4,084 (19.5) | 92,011 (21.8) |  | 4,263 (19.1) | 97,050 (21.4) |  |
 CSE | 878 (4.2) | 24,807 (5.9) |  | 894 (4.0) | 25,195 (5.6) |  |
 NVQ/HND/HNC | 1,869 (8.9) | 27,036 (6.4) |  | 1,969 (8.8) | 29,005 (6.4) |  |
 Other qualifications (nurse) | 1,220 (5.9) | 21,521 (5.1) |  | 1,302 (5.8) | 23,283 (5.1) |  |
 None | 6,359 (30.4) | 71,643 (16.9) |  | 6,873 (30.8) | 77,548 (17.1) |  |
 TDI (mean ± SD) | -0.97 ± 3.2 | -1.4 ± 3.0 |  < 0.001 | -1.8 ± 3.3 | -1.4 ± 3.1 |  < 0.001 |
Smoke status (%) |  |  |  < 0.001 |  |  |  < 0.001 |
 Never | 8,844 (41.8) | 237,242 (55.7) |  | 9,445 (41.8) | 255,109 (55.7) |  |
 Previous | 9,028 (42.6) | 143,604 (33.7) |  | 9,567 (42.3) | 153,341 (33.5) |  |
 Current | 3,138 (14.8) | 43,090 (10.1) |  | 3,403 (15.1) | 46,712 (10.2) |  |
 Missing value | 179 (0.8) | 2,405 (0.5) |  | 193 (0.8) | 2,528 (0.6) |  |
Alcohol drinker status (%) |  |  |  < 0.001 |  |  |  < 0.001 |
 Never | 1,201 (5.7) | 18,636 (4.4) |  | 1,273 (5.6) | 19,921 (4.4) |  |
 Previous | 1,209 (5.7) | 14,429 (3.4) |  | 1,302 (5.8) | 15,522 (3.4) |  |
 Current | 18,686 (88.2) | 391,901 (91.9) |  | 19,933 (88.2) | 420,804 (91.9) |  |
 Missing value | 93 (0.4) | 1,375 (0.3) |  | 100 (0.4) | 1,443 (0.3) |  |
 Diabetes baseline (%) | 3,013 (14.2) | 18,858 (4.4) |  < 0.001 | 3,176 (14.1) | 20,078 (4.4) |  < 0.001 |
 CVD baseline (%) | 5,210 (24.7) | 9,850 (2.3) |  < 0.001 | 5,573 (24.7) | 10,728 (2.4) |  < 0.001 |