Table 1 Baseline in patients’ characteristics
Characteristics | ALS cases(n = 14) | Controls(n = 126) | p value |
|---|---|---|---|
Age(years) | 59 (48–64) | 57 (50–64) | 0.84 |
Gender | |||
Male | 8 (57.14%) | 61 (48.41%) | 0.78 |
Female | 6 (42.86%) | 66 (51.59%) | |
Area of residence | |||
Urban | 9(64.29%) | 48(38.10%) | 0.11 |
Rural | 5(35.71%) | 78(61.90%) | |
Occupational activity | |||
Heavy | 4(28.57%) | 71(56.35%) | 0.9 |
Light | 10(71.43%) | 55(43.65%) | |
Site of onset | |||
Bulbar-onset ALS | 1 (12.60%) | ||
Spinal-onset ALS | 13 (87.40%) | ||
Lymphocyte | 1.76 (1.24–2.28) | 1.67 (1.41–2.04) | 0.86 |
Neutrophils | 3.27 (1.79–4.10) | 3.04 (2.40–4.03) | 0.74 |
Total cholesterol | 4.42 (3.89–5.63) | 1.20 (0.88–1.54) | < 0.01 |
Triglycerides | 1.16 (0.93–2.32) | 4.25 (3.61–4.84) | < 0.01 |
LDL | 2.76 (2.19–2.96) | 1.11 (0.95–1.37) | < 0.01 |
HDL | 1.16 (0.99–1.32) | 2.42 (2.03-3.00) | < 0.01 |
Serum albumin | 40.50 (38.25–42.53) | 39.15 (36.95–41.17) | 0.27 |
Alanine aminotransferase | 19.20 (13.25–29.35) | 19.00 (13.55-24.00) | 0.64 |
Aspartate transaminase | 22.15 (17.20–31.00) | 20.50 (16.95–22.45) | 0.36 |
Creatinine | 62.50 (51.73–75.25) | 58.50 (50.00–67.00) | 0.23 |
Uric acid | 318.00 (244.25–361.00) | 265.00 (221.25-308.75) | 0.03 |
Creatine kinase | 97.90 (50.88-195.33) | 65.90 (27.65–87.03) | 0.03 |
Glycosylated hemoglobin | 5.80 (5.65–5.95) | 5.70 (5.50–6.20) | 0.55 |
Serum superoxide dismutase | 147.45 (131.15-205.45) | 166.05 (142.98–192.30) | 0.63 |