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Table 3 Multivariable analysis: socio-demographic and clinical indicators as predictors for pulmonary tuberculosis among 1277 HIV-infected outpatients attending ART-clinics in South Kivu, DRC

From: Household air pollution and risk of pulmonary tuberculosis in HIV-Infected adults

Variables

Univariate Analysis

Multivariable Analysisb

N

cOR (95%CI)

P-value

N=956

aOR (95%CI)

P-value

Gender

1277

     

 Males

 

Ref

    

 Females

 

0.37 (0.28-0.48)

<0.001

 

0.39 (0.27-0·55)

<0.001

Marital Status

1277

     

 Married

 

Ref

    

 Separated

 

1.04 (0.71-1.51)

0.83

¨

¨

¨

 Single

 

0.83 (0.65-1.07)

0.15

¨

¨

¨

Level of Education

1277

     

 University

 

Ref

    

 High School

 

1.12 (0.61-2.05)

0.71

¨

¨

¨

 Primary School

 

1.31 (0.72-2.38)

0.37

¨

¨

¨

 No School

 

0.82 (0.42-1.60)

0.57

¨

¨

¨

Occupation

1277

     

 Public Function

 

Ref

    

 Famer

 

1.82 (0.70-4.73)

0.22

¨

¨

¨

 Private sector

 

0.85 (0.50-1.46)

0.56

¨

¨

¨

 Housekeeper

 

1.25 (0.77-2.03)

0.36

¨

¨

¨

 None at all

 

1.09 (0.65-1.83)

0.74

¨

¨

¨

Household Members

1181

     

 <5

 

Ref

    

 ≥5

 

1.05 (0.78-1.40)

0.76

¨

¨

¨

Alcohol

1238

     

 No

 

Ref

    

 Yes

 

1.02 (0.80-1.31)

0.88

¨

¨

¨

Tobacco Smoking

1221

     

 Never

 

Ref

    

 Evers

 

1.86 (1.26-2.26)

0.002

 

1.08 (0.67-1.74)

0.75

Second‑Hand Smoke

1159

     

 No

 

Ref

    

 Yes

 

1.58 (1.20-2.08)

0.001

 

1.41 (0.64-1.50)

0.8

CD4 at HIV diagnosis (cells/μL)

1277

     

 ≥500

 

Ref

    

 200-499

 

1.40 (0.92-2.11)

0.11

 

1.33 (0.83-2.14)

0.23

 <200

 

1.87 (1.24-2.82)

0.003

 

2.05 (1.28-3.31)

0.003

 Unknown

 

1.79 (1.21-2.66)

0.004

 

1.69 (1.06-2.70)

0.03

ART Duration (years)

1277

     

 ≥10

 

Ref

    

 5-9

 

0.84 (0.60-1.16)

0.30

 

0.86 (0.57-1.25)

0.40

 <5

 

0.85 (0.61-1.20)

0.38

 

0.73 (0.49-1.10)

0.14

 Unknown

 

1.10 (0.75-1.63)

0.63

 

1.15 (0.70-1.86)

0.59

Case Contact a

1155

     

 No

 

Ref

    

 Yes

 

0.97 (0.76-1.25)

0.84

 

1.1 (0.82-1.47)

0.54

  1. aCase contact was defined as a household member treated for pulmonary tuberculosis in the past five years.
  2. cOR crude odds ratio, aOR adjusted odds ratio, ART Antiretroviral therapy
  3. bVariables adjusted for in the model include gender, age, level of education, number of household members, tobacco smoking, second‑hand smoke, house roofing, house wall, CD4+ cell count, ART duration, and case contact. “..”: multivariable analysis was not performed as p-value ≤0.1