Exposure to cadmium and lead is associated with diabetic kidney disease in diabetic patients

Table 3 Multiplication interaction of Pb and Cd with DKD

Levels of Metals	N	OR (95%CI)	P for interaction
Metals in blood			0.044
Low BPb + Low BCd	916	1.00 (reference)
High BPb + Low BCd	763	1.90 (1.35, 2.68)
Low BPb + High BCd	702	1.51 (1.10, 2.08)
High BPb + High BCd	1382	2.58 (1.93, 3.45)
Metals in urine			0.071
Low UPb + Low UCd	240	1.00 (reference)
High UPb + Low UCd	288	1.20 (0.76, 1.88)
Low UPb + High UCd	219	1.91 (1.21, 3.02)
High UPb + High UCd	637	1.29 (0.88, 1.88)

Note: P50 was set as the cut-off point, and BPb, BCd, UPb, and UCd were divided into high and low exposure groups, 1 was high exposure, 0 was low exposure, and the relative risk (relative risk, RR) was replaced by the OR value calculated by the logistic regression model
Bold text indicates statistical significance

ISSN: 1476-069X