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Table 5 Weighted associations between prenatal dietary exposure to chemicals mixtures and the risk of allergic or respiratory diseases in early childhood

From: Prenatal dietary exposure to mixtures of chemicals is associated with allergy or respiratory diseases in children in the ELFE nationwide cohort

Mixture name

OR [95% CI]

Eczema

(n = 11,636)

Food allergy

(n = 11,635)

Wheezing

(n = 11,636)

Asthma

(n = 10,136)

TE-F-PAH

1.07 [1.02; 1.14]

1.02 [0.92; 1.14]

1.01 [0.95; 1.07]

0.98 [0.87; 1.11]

Mixt-3

0.99 [0.94; 1.03]

0.97 [0.86; 1.10]

1.00 [0.95; 1.05]

0.89 [0.80; 0.99]

Pest-1

1.01 [0.96; 1.06]

1.15 [1.06; 1.24]

0.98 [0.94; 1.03]

0.95 [0.86; 1.05]

Pest-3

1.01 [0.96; 1.06]

1.03 [0.95; 1.13]

1.00 [0.95; 1.06]

1.02 [0.92; 1.12]

PCB-BFR-Aso-MeHg

0.98 [0.94; 1.03]

1.03 [0.94; 1.14]

0.97 [0.92; 1.02]

0.88 [0.79; 0.98]

Pest-2

0.94 [0.89; 0.99]

0.93 [0.86; 1.02]

1.03 [0.98; 1.08]

0.99 [0.91; 1.09]

Mixt-4

0.97 [0.93; 1.02]

1.00 [0.90; 1.11]

1.04 [1.00; 1.09]

0.94 [0.86; 1.03]

PFAA-Ge-Li

1.00 [0.96; 1.05]

0.99 [0.91; 1.08]

1.03 [0.98; 1.08]

1.09 [0.99; 1.21]

  1. Values are odds ratios [95% CI] from logistic regression models including the eight mixtures simultaneously and adjusted for maternal characteristics (age, education level, migration status, employment, household income, rural residence, region of residence, number of older children in the household, smoking during pregnancy, diet quality), child and birth characteristics (sex, mode of delivery, family history of allergies), and variables related to study design (maternity size and recruitment wave). Abbreviations: TE-F-PAH trace elements-furans-polycyclic aromatic hydrocarbons, PCB-BFR-Aso-MeHg polychlorobiphenyls-brominated flame retardants-organic arsenic-methylmercury; Pest-1, pesticides-1; Pest-2, pesticides-2; Pest-3, pesticides-3; PFAA-Ge-Li, perfluoroalkyl acids-germanium-lithium; Mixt-3, mixture-3; Mixt-4, mixture-4
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Environmental Health

ISSN: 1476-069X