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Table 1 Aberrant Behavior Checklist (ABC) ADHD/noncompliance subscale and two subdomain scores by characteristics of 549 CHARGE children

From: Early childhood exposure to environmental phenols and parabens, phthalates, organophosphate pesticides, and trace elements in association with attention deficit hyperactivity disorder (ADHD) symptoms in the CHARGE study

Characteristics a

All children

(n = 549)

Aberrant Behavior Checklist (ABC)

ADHD/noncompliance

(n = 515)

Hyperactivity/impulsivity (n = 520)

Inattention

(n = 547)

 

Freq (%)

Median (IQR)

p-value b

Median (IQR)

p-value b

Median (IQR)

p-value b

Sex

  

0.48

 

0.41

 

0.72

 Male

440 (80.1)

7.0 (1.0, 18.8)

 

4.0 (1.0, 11.0)

 

2.0 (0.0, 3.8)

 

 Female

109 (19.9)

6.0 (1.0, 19.0)

 

3.0 (0.0, 10.0)

 

2.0 (0.0, 4.0)

 

Child’s birth year

  

0.008

 

0.004

 

0.008

 2000–2004

150 (27.3)

5.0 (1.0, 14.5)

 

3.0 (0.0, 10.0)

 

1.0 (0.0, 3.0)

 

 2005–2008

215 (39.2)

6.0 (1.0, 15.0)

 

3.0 (0.0, 10.0)

 

1.0 (0.0, 3.0)

 

 2009–2013

184 (33.5)

10.0 (3.0, 20.5)

 

6.0 (1.5, 13.5)

 

2.0 (0.0, 4.0)

 

Preterm birth (<  37 weeks)

  

0.06

 

0.08

 

0.07

 No

481 (89.4)

7.0 (1.0, 17.5)

 

4.0 (0.0, 10.0)

 

1.5 (0.0, 4.0)

 

 Yes

57 (10.6)

10.0 (3.3, 24.0)

 

6.0 (1.0, 14.3)

 

2.0 (1.0, 4.0)

 

Child’s race/ethnicity

  

0.01

 

0.01

 

0.04

 White (non-Hispanic)

271 (49.7)

5.0 (1.0, 16.0)

 

3.0 (0.0, 10.0)

 

1.0 (0.0, 3.0)

 

 Non-White (non-Hispanic)

115 (29.2)

10.0 (2.0, 24.5)

 

6.0 (1.0, 16.0)

 

2.0 (0.0, 4.0)

 

 Hispanic (any race)

159 (21.1)

7.5 (1.0, 15.0)

 

4.0 (1.0, 10.0)

 

2.0 (0.0, 3.0)

 

Mother’s age at delivery

  

0.004

 

0.009

 

0.008

 <  30 years

245 (44.6)

8.0 (1.0, 20.5)

 

4.0 (1.0, 13.0)

 

1.0 (0.0, 4.0)

 

 30–34 years

169 (30.8)

4.0 (0.5, 12.5)

 

2.0 (0.0, 8.0)

 

1.0 (0.0, 3.0)

 

 ≥ 35 years

135 (24.6)

10.0 (3.0, 17.0)

 

5.5 (1.3, 10.0)

 

2.0 (0.0, 4.0)

 

Maternal metabolic conditions

  

0.03

 

0.03

 

0.03

 Healthy weight/overweight

and no metabolic conditions

354 (66.3)

6.0 (1.0, 16.0)

 

3.0 (0.0, 10.0)

 

1.0 (0.0, 3.0)

 

 Obese or hypertensive

disorder/gestational diabetes

180 (33.7)

8.0 (2.0, 21.8)

 

6.0 (1.0, 14.0)

 

2.0 (0.0, 4.0)

 

Parity

  

< 0.001

 

< 0.001

 

< 0.001

 1

228 (42.8)

9.0 (3.0, 22.0)

 

6.0 (1.0, 14.0)

 

2.0 (0.0, 4.0)

 

 ≥ 2

305 (57.2)

5.0 (1.0, 14.0)

 

2.0 (0.0, 9.3)

 

1.0 (0.0, 3.0)

 

Highest education in household

  

< 0.001

 

< 0.001

 

< 0.001

 High school/GED or less

57 (10.4)

20.5 (8.5, 28.0)

 

12.0 (5.0, 19.0)

 

3.0 (2.0, 5.0)

 

 Some college credit

179 (32.6)

7.0 (1.0, 16.8)

 

4.0 (1.0, 10.0)

 

2.0 (0.0, 3.0)

 

 Bachelor’s degree or higher

313 (57.0)

5.0 (1.0, 15.0)

 

3.0 (0.0, 10.0)

 

1.0 (0.0, 3.0)

 

Homeowner

  

0.008

 

0.007

 

0.002

 No

166 (31.2)

9.0 (2.0, 22.3)

 

5.0 (1.0, 15.0)

 

2.0 (0.0, 4.0)

 

 Yes

366 (68.8)

6.0 (1.0, 15.8)

 

3.0 (0.0, 10.0)

 

1.0 (0.0, 3.0)

 

Diagnostic groups

  

< 0.001

 

< 0.001

 

< 0.001

 ASD

225 (41.0)

19.0 (10.0, 27.0)

 

11.0 (5.0, 18.0)

 

4.0 (2.0, 5.0)

 

 DD

236 (43.0)

8.5 (3.5, 19.0)

 

5.0 (2.0, 11.5)

 

2.0 (1.0, 4.0)

 

 TD

88 (16.0)

1.0 (0.0, 5.0)

 

1.0 (0.0, 3.0)

 

0.0 (0.0, 1.0)

 

Recruitment regional center

  

0.43

 

0.23

 

0.43

 Alta, Far Northern, Redwood Coast

268 (48.9)

7.0 (1.0, 16.0)

 

4.0 (0.0, 10.0)

 

1.0 (0.0, 3.0)

 

 North Bay, East Bay, San Andreas, Golden Gate

160 (29.2)

6.0 (1.0, 17.0)

 

3.0 (1.0, 10.0)

 

2.0 (0.0, 4.0)

 

 Valley Mt, Central Valley, Kern

120 (21.9)

10.0 (1.0, 21.0)

 

6.0 (1.0, 13.0)

 

2.0 (0.0, 4.0)

 
 

Median (IQR)

rsp c

p-value d

rsp c

p-value d

rsp d

p-value d

Child’s age at assessment

4.0 (3.4, 4.5)

0.12

0.005

0.13

0.004

0.11

0.01

  1. ADHD Attention-deficit/hyperactivity disorder, ASD Autism spectrum disorder, CHARGE Childhood Autism Risks from Genetics and Environment, DD Developmental delay, Freq Frequency, GED General educational development, IQR Interquartile range, rsp, Spearman correlation coefficient, TD Typical development
  2. aMissing (n): preterm birth (11), child’s race/ethnicity (5), maternal metabolic condition (16), parity (19), homeowner (21)
  3. bP-values from the Wilcox rank-sum test or the Kruskal-Wallis test
  4. cSpearman’s rank correlation coefficients between child’s age and ABC scores or DEP concentrations
  5. dP-values from the significance test of Spearman’s rank correlation coefficient