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Table 6 Sensitivity analysis of the association between cumulative respiratory silica exposure and ventilatory disorders using logistic regression

From: Dose-response relationship between lung function and chest imaging response to silica exposures in artificial stone manufacturing workers

 

Cumulative RCS exposure (mg/m3 x year)

Weighted tenure (year)

aOR

95% C.I.

p value

aOR

95% C.I.

p value

Model 1

      

Obstructive

1.08

(0.99–1.17)

0.086

1.03

(0.99–1.08)

0.122

Restrictive

1.09

(0.99–1.20)

0.065

1.03

(0.99–1.08)

0.105

Obstructive or restrictive

1.25

(1.05–1.49)

0.013

1.04

(1.01–1.08)

0.019

Model 2

      

Obstructive

1.08

(0.99–1.18)

0.075

1.05

(1.00-1.11)

0.056

Restrictive

1.09

(0.99–1.20)

0.067

1.03

(0.99–1.08)

0.106

Obstructive or restrictive

1.27

(1.06–1.52)

0.011

1.05

(1.01–1.10)

0.01

Model 3

      

Obstructive

1.08

(0.99–1.19)

0.072

1.06

(1.00-1.12)

0.049

Restrictive

1.09

(0.99–1.20)

0.089

1.03

(0.98–1.08)

0.182

Obstructive or restrictive

1.26

(1.06–1.51)

0.011

1.05

(1.01–1.10)

0.012

Model 4 (Never smokers)

      

Obstructive

1.00

(0.82–1.22)

0.970

-

-

-

Restrictive

1.10

(0.90–1.35)

0.339

1.02

(0.96–1.08)

0.587

Obstructive or restrictive

1.13

(0.89–1.43)

0.320

1.07

(1.00-1.13)

0.041

  1. 1. Obstructive: FEV1/FVC < LLN
  2. 2. Restrictive: FVC < LLN & FEV1/FVC > = LLN
  3. 3. Analyses of Model1 were adjusted for age, sex, body mass index
  4. 4. Analyses of Model2 were adjusted for age, sex, body mass index, education
  5. 5. Analyses of Model3 were adjusted for age, sex, body mass index, education, current smoking
  6. 6. Analyses of Model4 only included never smokers and were adjusted for age, sex, body mass index, education