Table 7 Sensitivity analysis of the association between cumulative respiratory silica exposure and lung function indices using linear regression
| Â | Cumulative RCS exposure (mg/m3 x year) | Weighted tenure (year) | ||||
|---|---|---|---|---|---|---|
Coefficient | 95% C.I. | p value | Coefficient | 95% C.I. | p value | |
Model1 | Â | Â | Â | Â | Â | Â |
FVC, % of prediction | -0.43 | (-0.83–0.03) | 0.037 | -0.11 | (-0.26-0.05) | 0.188 |
FEV1, % of prediction | -0.46 | (-0.81–0.11) | 0.01 | -0.13 | (-0.27-0.01) | 0.059 |
FEV1/FVC, % | -0.04 | (-0.26-0.19) | 0.748 | -0.04 | (-0.12-0.05) | 0.403 |
Model2 | Â | Â | Â | Â | Â | Â |
FVC, % of prediction | -0.4 | (-0.80-0.00) | 0.051 | -0.08 | (-0.25-0.09) | 0.352 |
FEV1, % of prediction | -0.43 | (-0.77–0.08) | 0.016 | -0.11 | (-0.25-0.04) | 0.154 |
FEV1/FVC, % | -0.03 | (-0.26-0.19) | 0.788 | -0.03 | (-0.12-0.06) | 0.469 |
Model3 | Â | Â | Â | Â | Â | Â |
FVC, % of prediction | -0.39 | (-0.80-0.02) | 0.059 | -0.07 | (-0.25-0.11) | 0.417 |
FEV1, % of prediction | -0.43 | (-0.79–0.08) | 0.016 | -0.11 | (-0.27-0.04) | 0.146 |
FEV1/FVC, % | -0.04 | (-0.27-0.19) | 0.737 | -0.04 | (-0.14-0.05) | 0.359 |
Model 4 (Never smokers) | Â | Â | Â | Â | Â | Â |
FVC, % of prediction | -0.60 | (-1.21-0.01) | 0.052 | -0.05 | (-0.31-0.21) | 0.709 |
FEV1, % of prediction | -0.49 | (-0.99-0.01) | 0.054 | -0.12 | (-0.33-0.10) | 0.272 |
FEV1/FVC, % | 0.06 | (-0.27-0.39) | 0.722 | -0.09 | (-0.22-0.05) | 0.198 |