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Table 9 Sensitivity and specificity of various combinations of clinical methods as comparing to silicosis defined as chest CT detected opacities

From: Dose-response relationship between lung function and chest imaging response to silica exposures in artificial stone manufacturing workers

 

All CT opacities

Only RO

Only GGO

Sensitivity

Specificity

Sensitivity

Specificity

Sensitivity

Specificity

Any clinical abnormality

      

 Symptom

58.3

75.0

44.4

54.6

66.7

72.7

 Spirometry

66.7

87.5

66.7

72.7

66.7

72.7

 CXR

16.7

100

22.2

100

22.2

100

 Dlco

41.7

50

55.6

63.6

55.6

63.6

 Symptom + Spirometry

91.7

75.0

88.9

54.6

100

63.6

 Spirometry + CXR

75.0

87.5

77.8

72.7

77.8

72.7

 Spirometry + Dlco

75.0

37.5

77.8

36.4

77.8

36.4

 Symptom + Spirometry + CXR

91.7

75.0

88.9

54.6

100

63.6

 Symptom + Spirometry + Dlco

91.7

37.5

88.9

27.3

100

36.4

 Symptom + Spirometry + CXR + Dlco

91.7

37.5

88.9

27.3

100

36.4

  1. All CT opacities includes round, irregular, ground glass, and large opacities
  2. RO: round opacities; GGO: ground glass opacities