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Table 1 Baseline characteristics of participants by rheumatoid arthritis (RA) status, NHANES 2003–2018 (N = 10,496)

From: Associations of per- and polyfluoroalkyl substances (PFAS) and their mixture with risk of rheumatoid arthritis in the U.S. adult population

Characteristic

Overall

Without RA

RA

p-value

Age, mean (SE)

47.03 (0.29)

46.59 (0.30)

57.52 (0.83)

< 0.0001

Age, n (%)

< 0.0001

20–39

3578 (36.76)

3534 (37.83)

44 (11.33)

 

40–59

3393 (38.23)

3194 (38.02)

199 (43.25)

 

≥ 60

3525 (25.01)

3196 (24.15)

329 (45.42)

 

BMI, mean (SE)

28.98 (0.11)

28.91 (0.11)

30.47 (0.40)

< 0.001

BMI, n (%)

< 0.001

25–30.0

3509 (33.49)

3350 (33.68)

159 (28.90)

 

< 25

3020 (30.16)

2892 (30.40)

128 (24.51)

 

≥ 30.0

3967 (36.35)

3682 (35.92)

285 (46.59)

 

Sex, n (%)

< 0.001

Male

5138 (48.75)

4901 (49.20)

237 (38.26)

 

Female

5358 (51.25)

5023 (50.80)

335 (61.74)

 

Ethnicity, n (%)

< 0.0001

Non-Hispanic White

4860 (70.79)

4610 (70.91)

250 (67.93)

 

Non-Hispanic Black

2147 (10.35)

1977 (10.05)

170 (17.50)

 

Mexican American

1646 (7.62)

1563 (7.67)

83 (6.34)

 

Other

1843 (11.24)

1774 (11.37)

69 (8.23)

 

Educational attainment, n (%)

< 0.0001

< High school

2541 (15.13)

2357 (14.84)

184 (21.93)

 

≥ High school

7955 (84.87)

7567 (85.16)

388 (78.07)

 

PIR, n (%)

< 0.0001

≤ 1.30

3196 (20.26)

2960 (19.88)

236 (29.29)

 

1.31–3.50

3968 (35.76)

3762 (35.62)

206 (39.13)

 

> 3.5

3332 (43.97)

3202 (44.50)

130 (31.58)

 

Alcohol consumption, n (%)

< 0.0001

Never

1488 (10.63)

1393 (10.51)

95 (13.50)

 

Former

1866 (14.43)

1721 (13.99)

145 (24.93)

 

Mild

3513 (36.60)

3322 (36.63)

191 (35.96)

 

Moderate

1587 (17.38)

1524 (17.65)

63 (11.01)

 

Heavy

2042 (20.96)

1964 (21.23)

78 (14.59)

 

Physical activity, n (%)

< 0.0001

No

5077 (41.60)

4712 (40.80)

365 (60.62)

 

Yes

5419 (58.40)

5212 (59.20)

207 (39.38)

 
  1. PIR: calculated by dividing family income by the poverty threshold
  2. Alcohol consumption: “Never” < 12 drinks in lifetime, “Former” ≥ 12 drinks in 1 year and no drink last year, or no drink last year but ≥ 12 drinks in lifetime, “Mild” < 1 drinks/d for female and < 2 drinks/d for male, “Moderate”, 1 to 2 drinks/d is for female and 2 to 3 drinks/d is for male, “Heavy”, ≥ 3 drinks/d is for female and ≥ 4 drinks/d is for male
  3. Physical activity: “Yes”, if engaging in moderate-intensity or vigorous-intensity sports, fitness, or recreational activities for > 10 min on a typical day; otherwise, “No”
  4. Abbreviations SE, standard error; BMI, body mass index; PIR, poverty income ratio