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Table 4 Odds ratios (OR) of amyotrophic lateral sclerosis associated with current proximity to any agricultural land or specific crop type within 100 m from residence (A), and with 20% continuous increase of any agricultural land or specific crop type (B)a

From: Pesticide exposure assessed through agricultural crop proximity and risk of amyotrophic lateral sclerosis

  Cases Controls Total (N = 3440) Cases Controls Emilia-Romagna (N = 2434) Cases Controls Sicily (N = 1006)
Crops Exp/Unexp Exp/Unexp OR (95% CI) Exp/Unexp Exp/Unexp OR (95% CI) Exp/Unexp Exp/Unexp OR (95% CI)
(A)
 Total agricultural land 290/413 1184/1553 0.92 (0.78, 1.09) 205/294 858/1077 0.88 (0.72, 1.07) 85/119 326/476 1.04 (0.76, 1.42)
 Vineyards 27/676 91/2646 1.16 (0.75, 1.80) 25/474 88/1847 1.11 (0.70, 1.75) 2/202 3/799 2.64 (0.44, 15.89)
 Orchards 46/657 181/2556 0.99 (0.71, 1.38) 9/490 97/1838 0.35 (0.17, 0.69) 37/167 84/718 1.89 (1.24, 2.89)
 Arable crops 203/500 826/1911 0.94 (0.78, 1.13) 191/308 756/1179 0.97 (0.79, 1.18) 12/192 70/732 0.65 (0.35, 1.23)
 Vegetable crops 3/700 5/2732 2.35 (0.56, 9.82) 2/497 4/1931 1.94 (0.35, 10.64) 1/203 1/801 3.95 (0.25, 63.36)
 Olive groves          6/198 11/791 2.18 (0.80, 5.96)
(B)
 Total agricultural land    1.01 (0.94, 1.09)    0.96 (0.88, 1.04)    1.35 (1.13, 1.63)
 Vineyards    1.15 (0.86, 1.54)    1.12 (0.83, 1.51)    Too high
 Orchards    0.93 (0.70, 1.24)    0.12 (0.02, 0.82)    1.52 (1.08, 2.13)
 Arable crops    0.98 (0.89, 1.08)    0.98 (0.89, 1.08)    1.01 (0.63, 1.61)
 Vegetable crops    4.00 (0.25, 63.9)    4.00 (0.25, 63.95)    -  
 Olive groves            5.01 (1.05, 23.97)
  1. aResults for dichotomous analysis expressed as crude OR for matched sets, and for continuous analysis using a conditional logistic regression model. Some estimates could not be computed because of too few exposed subjects