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Table 4 Environmental burdens of disease in terms of DALYs, economic value, and percent of GDP for major health outcomes based on attributable risks derived by WHO [29]a

From: Calculation of the disease burden associated with environmental chemical exposures: application of toxicological information in health economic estimation

Disease

DALYs (% fraction of total burden of disease in DALYs)

Environmental AF (%)

DALYs due to environmental risk factors

Economic cost ($billions)

% of Global GDP

Respiratory diseases

 Asthma

25,202,418 (0.9)

44 (26–53)

11,055,150

200 [124–500]

0.3 [0.2–0.8]

 Chronic obstructive pulmonary disease

92,376,604 (3.4)

35 (20–48)

32,280,160

400 [250–1000]

0.6 [0.4–1.5]

 Lower respiratory infections

146,863,685 (5.4)

35 (27–41)

51,752,605

530 [330–1320]

0.8 [0.5–2.1]

Cancers

 Lung cancer

38,535,303 (1.4)

36 (17–52)

13,902,105

285 [180–720]

0.5 [0.3–1.1]

 Other cancers

185,421,704 (6.8)

16 (7–41)

31,047,781

715 [450–1800]

1.1 [0.7–2.8]

Cardiovascular diseases

 Ischemic heart diseases

165,717,210 (6.0)

35 (26–46)

58,561,915

1065 [670–2660]

1.8 [1.1–4.2]

 Stroke

141,348,082 (5.2)

42 (24–53)

58,985,984

843 [527–2108]

1.3 [0.8–3.3]

Neuropsychiatric diseases

 Childhood behavioral disorders

6,208,771 (0.22)

12 (3–36)

742,156

12 [8–30]

0.02 [0.01–0.05]]]

Total

  

258,327,866

4050 [2500–10,140]

6.5 [4–15.8]

  1. aTotal DALYs, 2,743,857,491 (2012 values); Breakdown of DALYS for LMICs and HICs from WHO supplement [29]