Variables | Impaired eGFR | Non-impaired eGFR | Age and sex-adjusted ORsa (95%CI) |
---|---|---|---|
n = 225 | n = 1418 | ||
Age, median (IQR), year | 73 (13) | 61 (17) | 1.09 (1.07, 1.11) *** |
Male (%) | 63 (28.00) | 689 (48.59) | 1.88 (1.36, 2.60) *** |
BMI, median (IQR), kg/m2 | 24.72 (4.11) | 24.14 (4.12) | Â |
  < 18.5 | 12 (5.33) | 55 (3.88) | 2.34 (1.11, 4.93) * |
 18.5–24 | 70 (31.11) | 644 (45.42) | Reference |
 24–27 | 83 (36.89) | 469 (33.07) | 1.62 (1.13, 2.33) ** |
  > = 27 | 60 (26.67) | 250 (17.63) | 2.64 (1.76, 3.97) *** |
Education | |||
 Elementary school or lower | 83 (37.22) | 321 (22.75) | Reference |
 High school | 89 (39.91) | 625 (44.29) | 0.98 (0.68, 1.40) |
 College or higher | 51 (22.87) | 465 (32.96) | 0.73 (0.48, 1.11) |
Smokers (%) | 1103 (45.78) | 480 (33.85) | 1.19 (0.86, 1.65) |
Secondhand smoking exposure (%) | 69 (30.67) | 524 (37.16) | 0.92 (0.67, 1.28) |
Alcohol drinkers (%) | 76 (33.78) | 429 (30.25) | 0.83 (0.59, 1.17) |
Hypertension | 135 (60.00) | 413 (29.13) | 2.21 (1.62, 3.01) *** |
Type 2 Diabetes | 49 (21.78) | 122 (8.60) | 2.45 (1.65, 3.63) *** |
Uric acid, median (IQR), mg/dL | 6.10 (2.40) | 5.30 (1.80) | 1.48 (1.33, 1.66) *** |
  < 7 | 148 (66.07) | 1231 (87.43) | Reference |
  > =7 | 76 (33.93) | 177 (12.57) | 3.20 (2.24, 4.56) *** |
Insulin, median (IQR), μU/mL | 10.05 (10.70) | 7.30 (6.70) | 1.03 (1.02, 1.03) *** |
HOMA-IR, median (IQR) | 2.42 (3.30) | 1.66 (1.88) | 1.06 (1.04, 1.08) *** |
  < 1.9 | 80 (35.71) | 798 (56.68) | Reference |
  > =1.9 | 144 (64.29) | 610 (43.32) | 2.20 (1.61, 3.00) *** |
TC/HDL ratio, median (IQR) | 4.43 (1.35) | 4.13 (1.44) | 1.20 (1.02, 1.40) * |
  < 4 | 165 (73.66) | 1088 (76.94) | Reference |
  > =4 | 59 (26.34) | 326 (23.06) | 1.06 (0.75, 1.51) |
Folate in plasma, median (IQR), ng/mL | 8.68 (9.36) | 9.79 (8.20) | 0.98 (0.96, 1.01) |
  < 6 | 67 (29.78) | 302 (21.30) | 1.54 (1.09, 2.17) *** |
  > =6 | 158 (70.22) | 1116 (78.70) | Reference |
8-OHdG, median (IQR), ng/mg creatinine | 4.45 (3.57) | 4.89 (3.97) | 1.02 (0.98, 1.05) |