Table 2 The adjusted risk of all-cause and specific-cause mortality under individual and joint interventions on BLLs, UCd, and DII, using parametric g-formula with pooled logistic regression modelsa
| Â | All-cause mortality | Â | Cancer mortality | Â | Cardiovascular diseases mortality | |||
|---|---|---|---|---|---|---|---|---|
Interventions | Adjusted risk ratio (95% CI) | Adjusted risk difference (95% CI) | Â | Adjusted risk ratio (95% CI) | Adjusted risk difference (95% CI) | Â | Adjusted risk ratio (95% CI) | Adjusted risk difference (95% CI) |
No intervention (natural course) | 1 | 0 | Â | 1 | 0 | Â | 1 | 0 |
Lower BLLs = 5th percentile | 0.59 (0.44 to 0.81) | -3.32% (-5.02 to -1.43) |  | 0.59 (0.31 to 1.03) | -0.79% (-1.39 to 0.03) |  | 0.63 (0.38 to 1.17) | -0.97% (-1.87 to 0.49) |
Lower UCd = 5th percentile | 0.56 (0.41 to 0.79) | -3.56% (-5.29 to -1.67) |  | 0.92 (0.38 to 1.48) | -0.16% (-1.16 to 0.87) |  | 1.09 (0.61 to 1.56) | + 0.25% (-1.01 to 1.57) |
Lower both BLLs and UCd to 5th percentile | 0.35 (0.22 to 0.64) | -5.37% (-7.28 to -2.64) | Â | 0.49 (0.12 to 1.39) | -0.97% (-1.89 to 0.70) | Â | 0.43 (0.22 to 0.83) | -1.55% (-2.69 to -0.42) |
Anti-inflammatory diet = 75th percentile DII value | 0.96 (0.93 to 0.99) | -0.32% (-0.67 to -0.12) |  | 0.90 (0.72 to 0.98) | -0.18% (-0.65 to -0.04) |  | 0.93 (0.83 to 0.99) | -0.19% (-0.46 to -0.02) |
Lower both BLLs and UCd and anti-inflammatory diet | 0.32 (0.20 to 0.61) | -5.47% (-7.48 to -3.10) | Â | 0.19 (0.05 to 0.67) | -1.50% (-2.52 to -0.62) | Â | 0.33 (0.09 to 0.70) | -1.80% (-2.83 to -0.77) |
Higher BLLs and UCd = 95th percentile and pro-inflammatory diet (25th percentile DII) | 1.72 (1.37 to 2.21) | + 5.87% (2.71 to 10.53) |  | 1.39 (0.82 to 2.75) | + 0.79% (-0.43 to 3.51) |  | 1.22 (0.74 to 1.85) | + 0.59% (-0.77 to 2.58) |
Higher lead and cadmium levels and pro-inflammatory diet | 1 | 0 | Â | 1 | 0 | Â | 1 | 0 |
Lower both BLLs and UCd and anti-inflammatory diet | 0.19 (0.10 to 0.37) | -11.50% (-17.81 to -7.17) | Â | 0.15 (0.04 to 0.55) | -2.34% (-4.43 to -0.73) | Â | 0.26 (0.07 to 0.64) | -2.44% (-4.54 to -0.82) |