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Table 3 The adjusted risk of all-cause and specific-cause mortality under individual and joint interventions on BLLs, UCd, and fruits and vegetables daily servings, using parametric g-formula with pooled logistic regression modelsa

From: Potential benefits of joint hypothetical interventions on diet, lead, and cadmium on mortality in US adults

 

All-cause mortality

 

Cancer mortality

 

Cardiovascular diseases mortality

Interventions

Adjusted risk

ratio (95% CI)

Adjusted risk

difference (95% CI)

 

Adjusted risk

ratio (95% CI)

Adjusted risk

difference (95% CI)

 

Adjusted risk

ratio (95% CI)

Adjusted risk

difference (95% CI)

No intervention

(natural course)

1

0

 

1

0

 

1

0

Higher FV daily servings ≥ 5

0.97 (0.91 to 1.00)

-0.23% (-0.80 to 0.04)

 

0.95 (0.73 to 1.00)

-0.12% (-0.56 to -0.01)

 

0.97 (0.91 to 0.99)

-0.10% (-0.31 to -0.02)

Lower both BLLs and UCd and higher FV daily servings

0.32 (0.13 to 0.62)

-5.47% (-7.71 to -3.41)

 

0.30 (0.07 to 1.20)

-1.37% (-2.51 to 0.35)

 

0.32 (0.12 to 0.69)

-2.05% (-3.24 to -0.99)

Higher BLLs and UCd = 95th percentile and lower FV daily servings < 2

1.79 (1.28 to 2.49)

+ 6.77% (2.38 to 13.94)

 

1.44 (0.80 to 2.33)

+ 0.86% (-0.41 to 2.63)

 

1.34 (0.64 to 2.26)

+ 1.04% (-0.99 to 3.93)

Higher lead and cadmium levels and

lower FV daily servings

1

0

 

1

0

 

1

0

Lower both BLLs and UCd and higher FV daily servings

0.18 (0.08 to 0.36)

-12.64% (-19.16 to -7.73)

 

0.21 (0.04 to 0.88)

-2.18% (-4.54 to -0.14)

 

0.24 (0.06 to 0.78)

-3.13% (-6.17 to -0.52)

  1. a200 iterations were performed for bootstrapping the estimated 95% confidence interval