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Volume 21 Supplement 1

A Science-Based Agenda for Health-Protective Chemical Assessments and Decisions

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Publication of this supplement was funded by the JPB Foundation(A134084), Broad Reach/Tides(132805A), the Passport Foundation (A132316), NIEHS R01ES027051, NIEHS/USEPA P01ES02284, and NIEHS P30ES030284. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editor declares that they have no competing interests.

San Francisco, CA, USAN/A

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Edited by Daniele Mandrioli.


  1. The manufacture and production of industrial chemicals continues to increase, with hundreds of thousands of chemicals and chemical mixtures used worldwide, leading to widespread population exposures and result...

    Authors: Tracey J. Woodruff, Swati D. G. Rayasam, Daniel A. Axelrad, Patricia D. Koman, Nicholas Chartres, Deborah H. Bennett, Linda S. Birnbaum, Phil Brown, Courtney C. Carignan, Courtney Cooper, Carl F. Cranor, Miriam L. Diamond, Shari Franjevic, Eve C. Gartner, Dale Hattis, Russ Hauser…
    Citation: Environmental Health 2023 21(Suppl 1):132
  2. Understanding, characterizing, and quantifying human exposures to environmental chemicals is critical to protect public health. Exposure assessments are key to determining risks to the general population and f...

    Authors: Laura N. Vandenberg, Swati D. G. Rayasam, Daniel A. Axelrad, Deborah H. Bennett, Phil Brown, Courtney C. Carignan, Nicholas Chartres, Miriam L. Diamond, Rashmi Joglekar, Bhavna Shamasunder, Kristin Shrader-Frechette, Wilma A. Subra, Ken Zarker and Tracey J. Woodruff
    Citation: Environmental Health 2023 21(Suppl 1):121
  3. A key element of risk assessment is accounting for the full range of variability in response to environmental exposures. Default dose-response methods typically assume a 10-fold difference in response to chemi...

    Authors: Julia R. Varshavsky, Swati D. G. Rayasam, Jennifer B. Sass, Daniel A. Axelrad, Carl F. Cranor, Dale Hattis, Russ Hauser, Patricia D. Koman, Emily C. Marquez, Rachel Morello-Frosch, Catherine Oksas, Sharyle Patton, Joshua F. Robinson, Sheela Sathyanarayana, Peggy M. Shepard and Tracey J. Woodruff
    Citation: Environmental Health 2023 21(Suppl 1):133
  4. Human health risk assessment currently uses the reference dose or reference concentration (RfD, RfC) approach to describe the level of exposure to chemical hazards without appreciable risk for non-cancer healt...

    Authors: Greylin H. Nielsen, Wendy J. Heiger-Bernays, Jonathan I. Levy, Roberta F. White, Daniel A. Axelrad, Juleen Lam, Nicholas Chartres, Dimitri Panagopoulos Abrahamsson, Swati D. G. Rayasam, Rachel M. Shaffer, Lauren Zeise, Tracey J. Woodruff and Gary L. Ginsberg
    Citation: Environmental Health 2023 21(Suppl 1):129
  5. Hazard identification, risk assessment, regulatory, and policy activity are usually conducted on a chemical-by-chemical basis. Grouping chemicals into categories or classes is an underutilized approach that co...

    Authors: Maricel V. Maffini, Swati D. G. Rayasam, Daniel A. Axelrad, Linda S. Birnbaum, Courtney Cooper, Shari Franjevic, Patrick M. MacRoy, Keeve E. Nachman, Heather B. Patisaul, Kathryn M. Rodgers, Mark S. Rossi, Ted Schettler, Gina M. Solomon and Tracey J. Woodruff
    Citation: Environmental Health 2023 21(Suppl 1):120

Annual Journal Metrics

  • 2022 Citation Impact
    6.0 - 2-year Impact Factor
    7.0 - 5-year Impact Factor
    1.572 - SNIP (Source Normalized Impact per Paper)
    1.313 - SJR (SCImago Journal Rank)

    2023 Speed
    9 days submission to first editorial decision for all manuscripts (Median)
    119 days submission to accept (Median)

    2023 Usage 
    2,144,579 downloads
    5,304 Altmetric mentions