- Open Access
Current and future climate- and air pollution-mediated impacts on human health
© Doherty et al; licensee BioMed Central Ltd. 2009
Published: 21 December 2009
We describe a project to quantify the burden of heat and ozone on mortality in the UK, both for the present-day and under future emission scenarios.
Mortality burdens attributable to heat and ozone exposure are estimated by combination of climate-chemistry modelling and epidemiological risk assessment. Weather forecasting models (WRF) are used to simulate the driving meteorology for the EMEP4UK chemistry transport model at 5 km by 5 km horizontal resolution across the UK; the coupled WRF-EMEP4UK model is used to simulate daily surface temperature and ozone concentrations for the years 2003, 2005 and 2006, and for future emission scenarios. The outputs of these models are combined with evidence on the ozone-mortality and heat-mortality relationships derived from epidemiological analyses (time series regressions) of daily mortality in 15 UK conurbations, 1993-2003, to quantify present-day health burdens.
During the August 2003 heatwave period, elevated ozone concentrations > 200 μg m-3 were measured at sites in London and elsewhere. This and other ozone photochemical episodes cause breaches of the UK air quality objective for ozone. Simulations performed with WRF-EMEP4UK reproduce the August 2003 heatwave temperatures and ozone concentrations. There remains day-to-day variability in the high ozone concentrations during the heatwave period, which on some days may be explained by ozone import from the European continent.
Preliminary calculations using extended time series of spatially-resolved WRF-EMEP4UK model output suggest that in the summers (May to September) of 2003, 2005 & 2006 over 6000 deaths were attributable to ozone and around 5000 to heat in England and Wales. The regional variation in these deaths appears greater for heat-related than for ozone-related burdens.
Changes in UK health burdens due to a range of future emission scenarios will be quantified. These future emissions scenarios span a range of possible futures from assuming current air quality legislation is fully implemented, to a more optimistic case with maximum feasible reductions, through to a more pessimistic case with continued strong economic growth and minimal implementation of air quality legislation.
Elevated surface ozone concentrations during the 2003 heatwave period led to exceedences of the current UK air quality objective standards. A coupled climate-chemistry model is able to reproduce these temperature and ozone extremes. By combining model simulations of surface temperature and ozone with ozone-heat-mortality relationships derived from an epidemiological regression model, we estimate present-day and future health burdens across the UK. Future air quality legislation may need to consider the risk of increases in future heatwaves.
Air pollution is the environmental factor with the greatest impact on health in Europe . Tropospheric ozone is a major contributor to this health burden [2–4]. It is a trans-boundary pollutant, whose concentrations are affected not only by regional emissions of precursor species but also by long-range transport of air from upwind continents and the stratosphere. Despite regional legislative controls on emissions of ozone precursors, background ozone levels in Europe have increased  due to a rise in the global ozone background concentrations probably partly related to population growth and rapid industrialization in developing nations. Future greenhouse-gas induced climate warming and emissions of ozone precursors have the potential to adversely impact human health through enhanced heat and air pollution related mortalities. Change in climate will also increase the frequency and intensity of extreme climate events such as heat waves . Because ozone is generated by photochemical processes, its levels can rise substantially on hot sunny days, particularly when these are associated with slow-moving anticyclonic weather systems and stagnant air that traps emissions in the boundary layer. Hence, the direct health impacts of high temperatures can potentially be exacerbated due to high ozone levels.
One estimate suggests that 11/28% (with/without assumption of an O3 health threshold of 100 μg m-3) of the 2,045 deaths in England and Wales attributed to the heat wave of August 2003 may have been related to ozone . A more detailed analysis of nine French cities in the 2003 heat wave showed appreciable variation in the contribution of ozone and heat to mortality, suggesting the influence of environmental and population modifiers . One modelling study suggests that the temperatures experienced during the 2003 heatwave will become the average for summers from 2060 onwards .
Numerous studies have examined the effect of extreme temperatures or heatwaves on mortality rates controlling for air pollutants and epidemics [10, 11], or have investigated mortality associated with ozone exposure [12, 13]. However, the literature on the synergism between heat and ozone effects on human health is sparse [8, 14]. Furthermore, studies to date have generally been restricted to individual cities with limited spatial variation, since the majority of fixed-site monitors that provide temperature and ozone measurements are based in urban locations.
In our NERC-funded project we begin to address this issue by: (i) quantifying the interaction between ozone-heat and mortality across 15 UK conurbations; (ii) producing high resolution projections of present-day and future temperature and ozone concentrations over the UK; and (iii) combining results from (i) and (ii) to derive estimates of present-day and future health burdens for the entire UK. This approach permits the inclusion of rural locations, in which ozone concentrations are generally higher as compared to urban locations, in our analyses, as well as allow us to examine the full range of spatial heterogeneity from urban to rural areas across the UK for present-day. Furthermore, only a few studies have used climate and chemistry transport models to assess future impacts of climate or emission scenarios on human health [13, 15], and no study has yet been performed for the UK at fine-scale resolution.
Our overall project aim is to combine statistical epidemiological analyses of present-day mortality-ozone-temperature relationships based on data from 15 conurbations in England and Wales, with climate-chemistry model simulations to quantify the temperature-ozone mortality relationships across the entire UK at 5 km by 5 km horizontal resolution for present-day and under a range of future emission scenarios across the UK. The emissions scenarios span a range of possible emission futures from optimistic ("Maximum feasible reduction"), pessimistic (IPCC SRESA2) and current legislation . Present-day and future health burdens will be estimated and these will be evaluated within the context of adaptation and mitigation options.
Model representation of the physical and chemical state of the atmosphere at fine-scale resolution has been achieved through coupling of a numerical weather prediction model to a chemistry transport model. The domain used by both models covers the British Isles and parts of France, Denmark, Holland and Belgium. The two models operate at a horizontal resolution of 5 km × 5 km with ~20 vertical levels that extend from the surface up to 100 hPa (~16 km). The surface layer has depth 90 m. These regional-scale models are constrained by global meteorological and chemical boundary and initial conditions.
The chemistry transport model is EMEP4UK . The chemical scheme is identical to the extensively validated EMEP Unified Model  (Europe domain at 50 km × 50 km) which is widely used for air quality studies that inform EU policymakers. EMEP4UK operates at a much higher resolution needed for epidemiological studies. The chemical mechanism is based on the photochemistry of ozone, whereby ozone is produced by the oxidation of carbon monoxide (CO), methane (CH4) and non-methane hydrocarbons (NMHCs) in the presence of nitrogen oxides (NOx). Anthropogenic emissions of NOx, CO, NMHC, and particles PM2.5, PMCO (coarse particulate matter) are derived from the UK's National Atmospheric Emissions Inventories. Biogenic temperature-sensitive emissions of isoprene and monoterpenes (NMHCs) are also included.
We use a nesting approach in order to perform 5 km by 5 km resolution simulations. First, we use the EMEP Unified Model to simulate chemical transport across a much larger European domain at 50 km × 50 km resolution. The model used climatologically derived ozone boundary and initial conditions. These simulations provide the chemical initial conditions and boundary conditions for the EMEP4UK 5 km by 5 km resolution model simulations. The EMEP Unified model and EMEP4UK are both driven by meteorology from the Weather Research Forecast (WRF) model . WRF was also applied using a nesting approach whereby simulations were first performed at a 50 km by 50 km resolution for the larger European domain and these were used as boundary and initial conditions for further WRF simulations over the smaller UK domain at 5 km by 5 km resolution. These simulations provided the meteorological data to drive the EMEP European and EMEP4UK models at the required horizontal and vertical resolution. The re-analyses data from the US National Center for Environmental Prediction (NCEP)/National Center for Atmospheric Research (NCAR) Global Forecast System (GFS) were used as boundary conditions (6-hourly data assimilation) for the WRF European large-scale simulation.
Coupled WRF/EMEP4UK simulations have been performed for 2003, 2005 and 2006.
Ozone- and heat-related mortality burdens
Preliminary estimates of ozone- and heat-attributable deaths in England and Wales for combined years 2003, 2005 and 2006 using observed ozone heat-mortality relationships from Pattenden et al. combined with simulated ozone concentrations and temperature from EMEP4UK.
Number and percentage (95% CI) of deaths attributable to:
1.1 (0.5 - 1.7)
0.9 (0.8 - 1.1)
1.0 (0.5 - 1.5)
0.1 (-0.0- 0.3)
1.0 (0.5 - 1.5)
1.3 (1.1 - 1.5)
Yorks & Hum
1.0 (0.4 - 1.4)
0.6 (0.4 - 0.8)
1.1 (0.5 - 1.6)
0.9 (0.7 - 1.0)
1.1 (0.5 - 1.6)
1.0 (0.8 - 1.1)
1.2 (0.6 - 1.8)
0.5 (0.4 - 0.6)
1.2 (0.6 - 1.8)
1.9 (1.8 - 2.1)
1.3 (0.6 - 2.0)
0.8 (0.7 - 0.9)
1.3 (0.6 - 1.9)
0.8 (0.7 - 1.0)
1.2 (0.5 - 1.7)
0.9 (0.7 - 1.1)
By Population density:
1.1 (0.5 - 1.7)
1.1 (0.9 - 1.3)
1.1 (0.5 - 1.7)
0.6 (0.4 - 0.7)
1.5 (0.7 - 2.3)
0.1 (0.0 - 0.1)
1.3 (0.6 - 1.9)
0.6 (0.4 - 0.7)
1.1 (0.5 - 1.6)
2.3 (1.9 - 2.7)
1.0 (0.5 - 1.4)
1.6 (1.4 - 1.9)
0.8 (0.4 - 1.3)
0.1 (0.1 - 0.1)
1.0 (0.5 - 1.5)
0.0 (0.0 - 0.0)
1.6 (0.8 - 2.5)
2.5 (1.9 - 3.2)
> = 99th centile
2.7 (1.3 - 4.0)
16.7 (14.9- 18.5)
Burdens of disease or health/mortality burdens are defined here as the number of deaths that can be attributed to ozone or heat exposure. The regional ozone-heat-mortality relationships described above were combined with the outputs of surface ozone and temperature from EMPEK4UK climate-chemistry simulations for years 2003, 2005 and 2006 and data on the counts of deaths from all causes from the Office of National Statistics (ONS) for the same period. The data were stratified by region, population density, month and temperature band (< 92nd percentile, 92nd-99th percentile, >99th percentile) and were used to quantify ozone-heat related mortality burdens across England and Wales.
Future emission scenarios
To perform WRF/EMEP4UK simulations of ozone concentrations under future emissions scenarios we will apply scaling factors to anthropogenic emissions data currently used in EMEP4UK (as above) based on three future emission scenarios (optimistic, pessimistic and current legislation) and use compatible initial and boundary chemical conditions from existing global Chemistry transport model simulations performed with these three same future emission scenarios .
Results and discussion
Ozone and temperature extremes
Average daily-mean temperatures for the 15 conurbations ranged between 14.0-16.4°C, whilst the threshold temperatures for designation as a "hot day" within each conurbation, defined as the 95th percentile of 2-day mean temperature over the whole period 1993-2003, ranged between 17.6-19.8°C . In Greater London (the largest conurbation) May-Sept mean daily maximum 8-hour ozone concentration was 60 μg m-3, mean daily temperature was 16.2°C, and the temperature threshold for "hot day" designation was 19.8°C . The correlation coefficients between daily maximum 8-hour ozone and daily mean temperature for this May-Sept period were 0.39 for Greater London and 0.25 for the pooled dataset of all conurbations  indicating some evidence for a relationship between the two parameters.
Ozone and heat-related mortality burdens
Preliminary results of ozone and heat related mortality burdens for 2003, 2005 and 2006 combined are shown in Table 1. Overall, the number of deaths attributable to ozone appears slightly greater than that attributable to heat. Heat deaths show appreciable regional variation in terms of both the number and proportion of deaths attributable to heat, while the burden of ozone deaths was less varied in proportional terms. Proportionally more heat-deaths occur in urban settings, but the same is not true for ozone-related deaths. Ozone deaths appear to be greatest in the early warm-season (May, June) while heat deaths were greater in July and August, reflecting the warmer temperatures. Proportionally more ozone deaths occurred in periods of very high temperature.
assuming current legislation (CLE) and air quality standards apply in the future
calculating maximum feasible reductions (MFR) in the future (optimistic)
using the SRES A2 scenario which assumes regional economic growth, slower technological growth but rapidly continuous global population growth (pessimistic)
The first two of these emission scenarios were constructed at the International Institute for applied systems Analysis (IIASA), and the third of these by the Intergovernmental Panel on Climate change (IPCC) in its Special Report on Emissions Scenarios (SRES) . Results from an inter-comparison of 26 global atmospheric chemistry models driven with these three future emissions scenarios show that global tropospheric ozone burden decreases by 5% and increases by 6% and 15% in the MFR, CLE and SRES A2 scenarios respectively . The choice of scenario will undoubtedly affect surface ozone concentrations over the UK, the risk of exceedences of current UK air Quality objective standards and consequently the ozone-related health burdens .
A new coupled climate-chemistry model is able to reproduce observed temperature and ozone trends in the UK, including photochemical ozone episodes and heatwaves which often occur in tandem. By combining climate-chemistry model simulations of surface temperature and ozone, with epidemiological evidence on ozone-heat-mortality relationships derived from observed data we estimate present-day and, subsequently, future health burdens across the UK for emission scenarios that span a range of possible futures (current legislation, optimistic, pessimistic). Given the predictions of increasing temperatures, future air quality legislation may need to consider the risk of increased incidences of high ozone concentrations associated with future increases in heatwaves.
The peer review of this article can be found in Additional file1
Our project is funded under the Joint Environment & Human Health Programme (NERC, EA, Defra, MOD, MRC, The Wellcome Trust, ESRC, BBSRC, EPSRC and HPA), grant NE/E008593/1.
This article has been published as part of Environmental Health Volume 8 Supplement 1, 2009: Proceedings of the Joint Environment and Human Health Programme: Annual Science Day Conference and Workshop. The full contents of the supplement are available online at http://www.ehjournal.net/supplements/8/S1.
- EEA, Environment and Health: European Environment Agency report no 10/2005. 2005Google Scholar
- WHO: Health aspects of air pollution with particulate matter, ozone and nitrogen dioxide. Report on a WHO working group, EUR/03/5042688, Bonn. 2003Google Scholar
- Ito K, De Leon SF, Lippmann M: Associations Between Ozone and Daily Mortality: Analysis and Meta-Analysis. Epidemiology. 2005, 16: 446-457. 10.1097/01.ede.0000165821.90114.7f.View ArticleGoogle Scholar
- Bell ML, Peng RD, Dominici F: The Exposure-Response Curve for Ozone and Risk of Mortality and the Adequacy of Current Ozone Regulations. Environ Health Perspect. 2006, 114: 532-536.View ArticleGoogle Scholar
- Jonson JE, D Simpson H, Solberg S: Can we explain the trends in European ozone levels?. Atmos Chem Phys. 2006, 6: 51-66.View ArticleGoogle Scholar
- Cubasch U, et al: Projections of future climate change. Climate Change 2001: The Scientific Basis, Contribution of WG1 to the Third Assessment report of the IPCC. Edited by: Houghton JT, et al. 2001, Cambridge University Press, EnglandGoogle Scholar
- Stedman JR: The predicted number of air pollution related deaths in the UK during the August 2003 heatwave. Atmos Environ. 2004, 38: 1087-1090. 10.1016/j.atmosenv.2003.11.011.View ArticleGoogle Scholar
- Filleul L, et al: The Relation Between Temperature, Ozone and Mortality in 9 French Cities During the Heat Wave 2003. Environ Health Perspect. 2006, doi:10.1289/ehp.8328Google Scholar
- Stott PA, Stone DA, Allen MR: Human contribution to the European heatwave of 2003. Nature. 2004, 432: 610-613. 10.1038/nature03089.View ArticleGoogle Scholar
- Wilkinson P, McMichael T, Kovats S, Pattenden S, Hajat S, Armstrong B: International study of temperature and heatwaves on urban mortality in low and middle income countries (ISOTHERM). Epidemiology. 2002, 13: S81-Google Scholar
- O'Neill MS, Hajat S, Zanobetti A, Ramirez-Aguilar M, Schwartz J: Impact of control for air pollution and respiratory epidemics on the estimated associations of temperature and daily mortality. Int J Biometeorol. 2005, 50: 121-129. 10.1007/s00484-005-0269-z.View ArticleGoogle Scholar
- Anderson K: Air pollution and climate change. Health effects of climate change in the UK. 2002, Dept. of Health, London, 193-217.Google Scholar
- Knowlton K, et al: Assessing Ozone-Related Health Impacts under a Changing Climate. Environ Health Perspect. 2004, 112: 1557-1563.View ArticleGoogle Scholar
- Ren C, Williams GM, Mengersen K, Morawska L, Tong S: Does temperature modify short-term effects of ozone on total mortality in 60 large eastern US communities? -- An assessment using the NMMAPS data. Environment International. 2008, 34: 451-458. 10.1016/j.envint.2007.10.001.View ArticleGoogle Scholar
- West JJ, Fiore AM, Horowitz LW, Mauzerall DL: Global health benefits of mitigating ozone pollution with methane emission controls. PNAS. 2006, 103: 3988-3993. 10.1073/pnas.0600201103.View ArticleGoogle Scholar
- Dentener F, Stevenson D, Cofala J, Mechler R, Amann M, Bergamaschi P, Raes F, Derwent R: The impact of air pollutant and methane emission controls on tropospheric ozone and radiative forcing: CTM calculations for the period 1990-2030. Atmos Chem Phys. 2005, 5: 1731-1755.View ArticleGoogle Scholar
- Vieno M, Dore AJ, Stevenson DS, Doherty RM, Heal MR, Reis S, Hallsworth S, Tarrasón L, Wind P, Fowler D, Simpson D, Sutton MA: Modelling surface ozone during the 2003 heatwave in the UK. Atmos Chem Phys Discuss. 2009, 9: 19509-19544.View ArticleGoogle Scholar
- Simpson D, et al: Transboundary Acidification, Eutrofication and Ground Level Ozone in Europe. Part 1. Unified EMEP Model Description. (Eds.). EMEP/MSC-W Report 1/03. 2003, Norwegian Meteorological Institute, Blindern. NorwayGoogle Scholar
- WRF model description. [http://www.wrf-model.org]
- Pattenden S, Armstrong B, Milojevic A, Barratt B, Chalabi Z, Doherty R, Heal M, Kovats S, Wilkinson P: Ozone, heat and mortality in fifteen British conurbations. Occup Env Medicine. 2009Google Scholar
- Stevenson DS, et al: Multimodel ensemble simulations of present-day and near-future tropospheric ozone. J Geophys Res. 2006, 111: D08301-10.1029/2005JD006338. doi:10.1029/2005JD006338Google Scholar
- AQEG: Ozone in the United Kingdom. 2009, Fifth report of the Air Quality Expert group. Defra, London, ISBN 978-0-85521-184-4.Google Scholar
- Nakicenovic N, et al: Special Report on Emissions Scenarios: A Special Report of Working Group III of the Intergovernmental Panel on Climate Change. 2000, Cambridge Univ. Press, New York, 570-Google Scholar
This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.