Articles

Associations of acrylamide with non-alcoholic fatty liver disease in American adults: a nationwide cross-sectional study

Acrylamide (AA) is a toxicant to humans, but the association between AA exposure and the risk of non-alcoholic fatty liver disease (NAFLD) remains unclear. In this study, our objective is to examine the cross-...

Authors: Zhening Liu, Jinghua Wang, Shenghui Chen, Chengfu Xu and Yu Zhang

Associations between polyfluoroalkyl substance and organophosphate flame retardant exposures and telomere length in a cohort of women firefighters and office workers in San Francisco

Environmental chemical exposures can affect telomere length, which in turn has been associated with adverse health outcomes including cancer. Firefighters are occupationally exposed to many hazardous chemicals...

Authors: Cassidy Clarity, Jessica Trowbridge, Roy Gerona, Katherine Ona, Michael McMaster, Vincent Bessonneau, Ruthann Rudel, Heather Buren and Rachel Morello-Frosch

Multigenerational endometriosis : consequence of fetal exposure to diethylstilbestrol ?

Endometriosis, which affects 10–15 % of women of reproductive age, is an estrogen-driven condition influenced by environmental and genetic factors. Exposition to estrogen-like endocrine-disrupting chemicals (E...

Authors: Laura Gaspari, Marie-Odile Soyer-Gobillard, Françoise Paris, Nicolas Kalfa, Samir Hamamah and Charles Sultan

Human-Biomonitoring derived exposure and Daily Intakes of Bisphenol A and their associations with neurodevelopmental outcomes among children of the Polish Mother and Child Cohort Study

Bisphenol A (BPA) is an industrial chemical mostly used in the manufacture of plastics, resins and thermal paper. Several studies have reported adverse health effects with BPA exposures, namely metabolic disor...

Authors: Mercè Garí, Rebecca Moos, Daniel Bury, Monika Kasper-Sonnenberg, Agnieszka Jankowska, Aleksandra Andysz, Wojciech Hanke, Dennis Nowak, Stephan Bose-O’Reilly, Holger M. Koch and Kinga Polanska

Quantifying the short-term effects of air pollution on health in the presence of exposure measurement error: a simulation study of multi-pollutant model results

Most epidemiological studies estimate associations without considering exposure measurement error. While some studies have estimated the impact of error in single-exposure models we aimed to quantify the effec...

Authors: Dimitris Evangelopoulos, Klea Katsouyanni, Joel Schwartz and Heather Walton

Short-term PM_2.5 and cardiovascular admissions in NY State: assessing sensitivity to exposure model choice

Air pollution health studies have been increasingly using prediction models for exposure assessment even in areas without monitoring stations. To date, most studies have assumed that a single exposure model is...

Authors: Mike Z. He, Vivian Do, Siliang Liu, Patrick L. Kinney, Arlene M. Fiore, Xiaomeng Jin, Nicholas DeFelice, Jianzhao Bi, Yang Liu, Tabassum Z. Insaf and Marianthi-Anna Kioumourtzoglou

Human detection thresholds of DC, AC, and hybrid electric fields: a double-blind study

In the course of the ongoing transition of electric energy systems, transmission corridors are often upgraded to higher voltages and other technologies leading to another quality of human exposure. The study a...

Authors: Michael Kursawe, Dominik Stunder, Thomas Krampert, Andrea Kaifie, Sarah Drießen, Thomas Kraus and Kathrin Jankowiak

Environmental epidemiology in a crossfire

Two tendencies have emerged in environmental epidemiology that hamper the translation of research findings into prevention of environmental hazards. One is the increased focus on highlighting weaknesses of epi...

Authors: Ruth A. Etzel, Philippe Grandjean and David M. Ozonoff

Toolkit for detecting misused epidemiological methods

Critical knowledge of what we know about health and disease, risk factors, causation, prevention, and treatment, derives from epidemiology. Unfortunately, its methods and language can be misused and improperly...

Authors: Colin L. Soskolne, Shira Kramer, Juan Pablo Ramos-Bonilla, Daniele Mandrioli, Jennifer Sass, Michael Gochfeld, Carl F. Cranor, Shailesh Advani and Lisa A. Bero

Ultrafine particle levels measured on board short-haul commercial passenger jet aircraft

Airline crew members report adverse health effects during and after inhalation exposure to engine oil fumes sourced to the air supply system onboard commercial and military aircraft. Most investigations into t...

Authors: Susan Michaelis, Tristan Loraine and C. V. Howard

Bisphenol-A exposure and risk of breast and prostate cancer in the Spanish European Prospective Investigation into Cancer and Nutrition study

Bisphenol A (BPA) is an endocrine disruptor that it is present in numerous products of daily use. The aim of this study was to assess the potential association of serum BPA concentrations and the risk of incid...

Authors: Elena Salamanca-Fernández, Miguel Rodríguez-Barranco, Pilar Amiano, Josu Delfrade, Maria Dolores Chirlaque, Sandra Colorado, Marcela Guevara, Ana Jimenez, Juan Pedro Arrebola, Fernando Vela, Nicolás Olea, Antonio Agudo and Maria-José Sánchez

Commentary: Novel strategies and new tools to curtail the health effects of pesticides

Flaws in the science supporting pesticide risk assessment and regulation stand in the way of progress in mitigating the human health impacts of pesticides. Critical problems include the scope of regulatory tes...

Authors: Charles Benbrook, Melissa J. Perry, Fiorella Belpoggi, Philip J. Landrigan, Michelle Perro, Daniele Mandrioli, Michael N. Antoniou, Paul Winchester and Robin Mesnage

Endocrine disrupting chemical-associated hair product use during pregnancy and gestational age at delivery: a pilot study

Prenatal endocrine disrupting chemical (EDC) exposure has been associated with increased risk of preterm birth. Non-Hispanic Black women have higher incidence of preterm birth compared to other racial/ethnic g...

Authors: Emma V. Preston, Victoria Fruh, Marlee R. Quinn, Michele R. Hacker, Blair J. Wylie, Karen O’Brien, Shruthi Mahalingaiah and Tamarra James-Todd

Short term physician visits and medication prescriptions for allergic disease associated with seasonal tree, grass, and weed pollen exposure across the United States

While year-round exposure to pollen is linked to a large burden of allergic diseases, location-specific risk information on pollen types and allergy outcomes are limited. We characterize the relationship betwe...

Authors: Shubhayu Saha, Ambarish Vaidyanathan, Fiona Lo, Claudia Brown and Jeremy J. Hess

Development of health-based exposure limits for radiofrequency radiation from wireless devices using a benchmark dose approach

Epidemiological studies and research on laboratory animals link radiofrequency radiation (RFR) with impacts on the heart, brain, and other organs. Data from the large-scale animal studies conducted by the U.S....

Authors: Uloma Igara Uche and Olga V. Naidenko

Acute health effects associated with satellite-determined cyanobacterial blooms in a drinking water source in Massachusetts

The occurrence of cyanobacterial blooms in freshwater presents a threat to human health. However, epidemiological studies on the association between cyanobacterial blooms in drinking water sources and human he...

Authors: Jianyong Wu, Elizabeth D. Hilborn, Blake A. Schaeffer, Erin Urquhart, Megan M. Coffer, Cynthia J. Lin and Andrey I. Egorov

Effects of exposure to surrounding green, air pollution and traffic noise with non-accidental and cause-specific mortality in the Dutch national cohort

Everyday people are exposed to multiple environmental factors, such as surrounding green, air pollution and traffic noise. These exposures are generally spatially correlated. Hence, when estimating association...

Authors: Jochem O. Klompmaker, Nicole A. H. Janssen, Lizan D. Bloemsma, Marten Marra, Erik Lebret, Ulrike Gehring and Gerard Hoek

Exposure to environmental phenols and parabens, and relation to body mass index, eczema and respiratory outcomes in the Norwegian RHINESSA study

Many phenols and parabens are applied in cosmetics, pharmaceuticals and food, to prevent growth of bacteria and fungi. Whether these chemicals affect inflammatory diseases like allergies and overweight is larg...

Authors: Hilde Kristin Vindenes, Cecilie Svanes, Stein Håkon Låstad Lygre, Francisco Gomez Real, Tamar Ringel-Kulka and Randi Jacobsen Bertelsen

Correction to: Associations between prenatal exposure to cadmium and lead with neural tube defect risks are modified by single-nucleotide polymorphisms of fetal MTHFR and SOD2: a case–control study

Authors: Mengyuan Liu, Jinhui Yu, Zaiming Su, Ying Sun, Yaqiong Liu, Qing Xie, Zhiwen Li, Linlin Wang, Jie Zhang, Lei Jin and Aiguo Ren

Exposure to arsenic at different life-stages and DNA methylation meta-analysis in buccal cells and leukocytes

Arsenic (As) exposure through drinking water is a global public health concern. Epigenetic dysregulation including changes in DNA methylation (DNAm), may be involved in arsenic toxicity. Epigenome-wide associa...

Authors: Anne K. Bozack, Philippe Boileau, Linqing Wei, Alan E. Hubbard, Fenna C. M. Sillé, Catterina Ferreccio, Johanna Acevedo, Lifang Hou, Vesna Ilievski, Craig M. Steinmaus, Martyn T. Smith, Ana Navas-Acien, Mary V. Gamble and Andres Cardenas

Portable HEPA filter air cleaner use during pregnancy and children’s behavior problem scores: a secondary analysis of the UGAAR randomized controlled trial

Developmental exposure to particulate matter (PM) air pollution may impair children’s behaviors. Our objectives were to quantify the impact of reducing indoor PM using portable HEPA filter air cleaners during ...

Authors: Undarmaa Enkhbat, Enkhjargal Gombojav, Chimeglkham Banzrai, Sarangerel Batsukh, Buyantushig Boldbaatar, Enkhtuul Enkhtuya, Chimedsuren Ochir, David C. Bellinger, Bruce P. Lanphear, Lawrence C. McCandless and Ryan W. Allen

Association of indoor microbial aerosols with respiratory symptoms among under-five children: a systematic review and meta-analysis

Despite the recognition of the importance of indoor microbial exposures on children’s health, the role of different microbial agents in development and aggravation of respiratory symptoms and diseases is only ...

Authors: Adekunle Gregory Fakunle, Nkosana Jafta, Rajen N. Naidoo and Lidwien A. M. Smit

Mixture effects of prenatal exposure to per- and polyfluoroalkyl substances and polybrominated diphenyl ethers on maternal and newborn telomere length

Per- and polyfluoroalkyl substances (PFAS) and polybrominated diphenyl ethers (PBDEs) are endocrine disrupting chemicals with widespread exposures across the U.S. given their abundance in consumer products. PF...

Authors: Stephanie M. Eick, Dana E. Goin, Lara Cushing, Erin DeMicco, June-Soo Park, Yunzhu Wang, Sabrina Smith, Amy M. Padula, Tracey J. Woodruff and Rachel Morello-Frosch

Dose–response evaluation of urinary cadmium and kidney injury biomarkers in Chinese residents and dietary limit standards

Cadmium (Cd) is a common heavy metal that mainly causes renal damage. There is a lack of research on the large-scale and systematic evaluation of the association between urinary Cd (U-Cd) and various effect bi...

Authors: Ying Qing, Jiaqi Yang, Yuanshen Zhu, Yongzhen Li, Weiwei Zheng, Min Wu and Gengsheng He

Associations between exposure to perfluoroalkyl substances and body fat evaluated by DXA and MRI in 109 adolescent boys

Exposure to perfluoroalkyl substances (PFASs) has been associated with changes in body mass index and adiposity, but evidence is inconsistent as study design, population age, follow-up periods and exposure lev...

Authors: Mathilde Lolk Thomsen, Louise Scheutz Henriksen, Jeanette Tinggaard, Flemming Nielsen, Tina Kold Jensen and Katharina M. Main

Effects of air pollution exposure on social behavior: a synthesis and call for research

There is a growing literature from both epidemiologic and experimental animal studies suggesting that exposure to air pollution can lead to neurodevelopmental and neuropsychiatric disorders. Here, we suggest t...

Authors: Chelsea A. Weitekamp and Hans A. Hofmann

Household air pollution, ultrasound measurement, fetal biometric parameters and intrauterine growth restriction

Low birthweight, intrauterine growth restriction (IUGR) and perinatal mortality have been associated with air pollution. However, intervention studies that use ultrasound measurements to assess the effects of ...

Authors: Anindita Dutta, Donee Alexander, Theodore Karrison, Oludare Morhasson-Bello, Nathaniel Wilson, Omolola Mojisola Atalabi, Damilola Adu, Tope Ibigbami, Samuel Adekunle, Dayo Adepoju, John Olamijulo, Omolola Akinwunmi, Oluniyi S. Afolabi, Oluwafunmilade Deji-Abiodun, Babatunde Adedokun, Briseis Aschebrook-Kilfoy…

Occupational exposure to polycyclic aromatic hydrocarbons and risk of prostate cancer

Several industries entailing exposure to polycyclic aromatic hydrocarbons (PAHs) are known or suspected carcinogens. A handful of studies have assessed the role of PAHs exposure in prostate cancer risk, but no...

Authors: Christine Barul and Marie-Elise Parent

Ambient PM gross β-activity and glucose levels during pregnancy

Exposure to ionizing radiation has been associated with insulin resistance and type 2 diabetes. In light of recent work showing an association between ambient particulate matter (PM) gross β-activity and gesta...

Authors: Veronica A. Wang, Tamarra James-Todd, Michele R. Hacker, Karen E. O’Brien, Blair J. Wylie, Russ Hauser, Paige L. Williams, Andrea Bellavia, Marlee Quinn, Thomas F. McElrath and Stefania Papatheodorou

Preterm birth and PM_2.5 in Puerto Rico: evidence from the PROTECT birth cohort

Preterm birth (PTB, birth before 37 weeks of gestation) has been associated with adverse health outcomes across the lifespan. Evidence on the association between PTB and prenatal exposure to air pollutants is ...

Authors: Kipruto Kirwa, Zlatan Feric, Justin Manjourides, Akram Alshawabekeh, Carmen Milagros Velez Vega, José F. Cordero, John D. Meeker and Helen H. Suh

Prenatal exposure to consumer product chemical mixtures and size for gestational age at delivery

While fetal growth is a tightly regulated process, it is sensitive to environmental exposures that occur during pregnancy. Many commonly used consumer products contain chemicals that can disturb processes unde...

Authors: P. A. Bommarito, B. M. Welch, A. P. Keil, G. P. Baker, D. E. Cantonwine, T. F. McElrath and K. K. Ferguson

Prenatal exposure to ambient air pollutants and early infant growth and adiposity in the Southern California Mother’s Milk Study

Prior epidemiological and animal work has linked in utero exposure to ambient air pollutants (AAP) with accelerated postnatal weight gain, which is predictive of increased cardiometabolic risk factors in child...

Authors: William B. Patterson, Jessica Glasson, Noopur Naik, Roshonda B. Jones, Paige K. Berger, Jasmine F. Plows, Hilary A. Minor, Frederick Lurmann, Michael I. Goran and Tanya L. Alderete

Associations between prenatal exposure to cadmium and lead with neural tube defect risks are modified by single-nucleotide polymorphisms of fetal MTHFR and SOD2: a case–control study

Prenatal exposure to heavy metals is implicated in the etiology of birth defects. We investigated whether concentrations of cadmium (Cd) and lead (Pb) in umbilical cord tissue are associated with risk for neur...

Authors: Mengyuan Liu, Jinhui Yu, Zaiming Su, Ying Sun, Yaqiong Liu, Qing Xie, Zhiwen Li, Linlin Wang, Jie Zhang, Lei Jin and Aiguo Ren

Annual dementia incidence and monetary burden attributable to fine particulate matter (PM_2.5) exposure in Sweden

Alzheimer’s disease (AD) and other dementias currently represent the fifth most common cause of death in the world, according to the World Health Organization, with a projected future increase as the proportio...

Authors: Hedi Katre Kriit, Bertil Forsberg, Daniel Oudin Åström and Anna Oudin

Associations between blood cadmium and endocrine features related to PCOS-phenotypes in healthy women of reproductive age: a prospective cohort study

Cadmium is an endocrine disrupting chemical that affects the hypothalamic-pituitary-gonadal axis. Though evidence suggests its potential role in altering androgen synthesis and metabolic pathways that are char...

Authors: Keewan Kim, Anna Z. Pollack, Carrie J. Nobles, Lindsey A. Sjaarda, Jessica R. Zolton, Jeannie G. Radoc, Enrique F. Schisterman and Sunni L. Mumford

A pathway level analysis of PFAS exposure and risk of gestational diabetes mellitus

Per- and polyfluoroalkyl substances (PFAS) have been found to be associated with gestational diabetes mellitus (GDM) development, a maternal health disorder in pregnancy with negative effects that can extend b...

Authors: Rahel L. Birru, Hai-Wei Liang, Fouzia Farooq, Megha Bedi, Maisa Feghali, Catherine L. Haggerty, Dara D. Mendez, Janet M. Catov, Carla A. Ng and Jennifer J. Adibi

Letter to the Editor: Cancer rates not explained by smoking: how to investigate a single county

Authors: Douglas J. Myers, Polly Hoppin, Molly Jacobs, Richard Clapp and David Kriebel

Clinical outcomes associated with long-term exposure to airborne particulate pollution in kidney transplant recipients

Researchers have yet to investigate the specific association between 10-μm particulate matter (PM10) levels and the risk of graft failure, kidney disease, or the functional decline of transplanted kidneys, in ...

Authors: Yong Chul Kim, Ejin Kim, Jiyun Jung, Jae Yoon Park, Hajeong Lee, Dong Ki Kim, Yon Su Kim, Chun Soo Lim, Jung Pyo Lee and Ho Kim

Maternal bisphenol urine concentrations, fetal growth and adverse birth outcomes: A population-based prospective cohort

Exposure to bisphenols may affect fetal growth and development. The trimester-specific effects of bisphenols on repeated measures of fetal growth remain unknown. Our objective was to assess the associations of...

Authors: Chalana M. Sol, Charissa van Zwol - Janssens, Elise M. Philips, Alexandros G. Asimakopoulos, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Vincent W. V. Jaddoe, Leonardo Trasande and Susana Santos

Risk of cardiovascular mortality, stroke and coronary heart mortality associated with aircraft noise around Congonhas airport, São Paulo, Brazil: a small-area study

Noise pollution is increasingly recognised as a public health hazard, yet limited evidence is available from low- and middle-income countries (LMIC), particularly for specific sources. Here, we investigated th...

Authors: Aina Roca-Barceló, Adelaide Nardocci, Breno Souza de Aguiar, Adeylson G. Ribeiro, Marcelo Antunes Failla, Anna L. Hansell, Maria Regina Cardoso and Frédéric B. Piel

Characterizing environmental geographic inequalities using an integrated exposure assessment

At a regional or continental scale, the characterization of environmental health inequities (EHI) expresses the idea that populations are not equal in the face of pollution. It implies an analysis be conducted...

Authors: Julien CAUDEVILLE, Corentin REGRAIN, Frederic TOGNET, Roseline BONNARD, Mohammed GUEDDA, Celine BROCHOT, Maxime BEAUCHAMP, Laurent LETINOIS, Laure MALHERBE, Fabrice MARLIERE, Francois LESTREMAU, Karen CHARDON, Veronique BACH and Florence Anna ZEMAN

Correction to: Air pollution, methane super-emitters, and oil and gas wells in Northern California: the relationship with migraine headache prevalence and exacerbation

Authors: Holly Elser, Rachel Morello-Frosch, Alice Jacobson, Alice Pressman, Marianthi-Anna Kioumourtzoglou, Richard Reimer and Joan A. Casey

Joint effects of ethnic enclave residence and ambient volatile organic compounds exposure on risk of gestational diabetes mellitus among Asian/Pacific Islander women in the United States

Asian/Pacific Islander (API) communities in the United States often reside in metropolitan areas with distinct social and environmental attributes. Residence in an ethnic enclave, a socially distinct area, is ...

Authors: Andrew D. Williams, Sandie Ha, Edmond Shenassa, Lynne C. Messer, Jenna Kanner and Pauline Mendola

Time-series analysis of daily ambient temperature and emergency department visits in five US cities with a comparison of exposure metrics derived from 1-km meteorology products

Ambient temperature observations from single monitoring stations (usually located at the major international airport serving a city) are routinely used to estimate heat exposures in epidemiologic studies. This...

Authors: Nikita Thomas, Stefanie T. Ebelt, Andrew J. Newman, Noah Scovronick, Rohan R. D’Souza, Shannon E. Moss, Joshua L. Warren, Matthew J. Strickland, Lyndsey A. Darrow and Howard H. Chang

Spatio-temporal associations of air pollutant concentrations, GP respiratory consultations and respiratory inhaler prescriptions: a 5-year study of primary care in the borough of Lambeth, South London

Although the associations of outdoor air pollution exposure with mortality and hospital admissions are well established, few previous studies have reported on primary care clinical and prescribing data. We ass...

Authors: Mark Ashworth, Antonis Analitis, David Whitney, Evangelia Samoli, Sofia Zafeiratou, Richard Atkinson, Konstantina Dimakopoulou, Sean Beavers, Joel Schwartz and Klea Katsouyanni

Emulating causal dose-response relations between air pollutants and mortality in the Medicare population

Fine particulate matter (PM_2.5), ozone (O₃), and nitrogen dioxide (NO₂) are major air pollutants that pose considerable threats to human health. However, what has been mostly missing in air pollution epidemiology...

Authors: Yaguang Wei, Mahdieh Danesh Yazdi, Qian Di, Weeberb J. Requia, Francesca Dominici, Antonella Zanobetti and Joel Schwartz

Research on developing environmental ethics in pharmacists’ activities

Authors of various backgrounds are preoccupied with the meaning of environmental ethics, which refers to specific values, norms, attitudes, and practices with respect to all beings and elements of nature. Many...

Authors: Alexandra Toma and Ofelia Crişan

Day time, night time, over time: geographic and temporal uncertainty when linking event and contextual data

The growth of geolocated data has opened the door to a wealth of new research opportunities in the health fields. One avenue of particular interest is the relationship between the spaces where people spend tim...

Authors: David C. Folch, Christopher S. Fowler and Levon Mikaelian

Maternal methylmercury exposure through rice ingestion and child neurodevelopment in the first three years: a prospective cohort study in rural China

Rice is an important dietary source for methylmercury; however, rice does not contain the same beneficial nutrients as fish. Our main objective was to assess associations of prenatal methylmercury exposure thr...

Authors: Sarah E. Rothenberg, Susan A. Korrick, Jihong Liu, Yanfen Nong, Hua Nong, Chuan Hong, Eva P. Trinh, Xu Jiang, Fred J. Biasini and Fengxiu Ouyang

Occupational exposure to glyphosate and risk of lymphoma:results of an Italian multicenter case-control study

The International Agency for Research on Cancer (IARC) recently classified glyphosate, the most used herbicide worldwide, as a probable human carcinogen. We inquired into the association between occupational e...

Authors: Federico Meloni, Giannina Satta, Marina Padoan, Andrea Montagna, Ilaria Pilia, Alessandra Argiolas, Sara Piro, Corrado Magnani, Angela Gambelunghe, Giacomo Muzi, Giovanni Maria Ferri, Luigi Vimercati, Roberta Zanotti, Aldo Scarpa, Mariagrazia Zucca, Sara De Matteis…