Articles

Associations between indoor environmental quality in schools and symptom reporting in pupil-administered questionnaires

The associations between indoor environmental quality (IEQ) in homes and symptom reporting of children have been extensively studied, but only few large-scale studies have been done in schools. We examined ass...

Authors: Kateryna Savelieva, Tero Marttila, Jussi Lampi, Sari Ung-Lanki, Marko Elovainio and Juha Pekkanen

Cumulative solar ultraviolet radiation exposure and basal cell carcinoma of the skin in a nationwide US cohort using satellite and ground-based measures

Basal cell carcinoma of the skin (BCC) is the most common cancer in populations of European ancestry. Although consistently linked with basal cell carcinoma of the skin in case-control studies, few prospective...

Authors: Mark P. Little, Martha S. Linet, Michael G. Kimlin, Terrence Lee, Zaria Tatalovich, Alice J. Sigurdson and Elizabeth K. Cahoon

Response to the “Letter to the Editor” by Gabor Mezei et al., Comments on Vimercati et al., 2019, “Asbestos exposure and malignant mesothelioma of the tunica vaginalis testis: a systematic review and the experience of the Apulia (Southern Italy) mesothelioma register”

Authors: Luigi Vimercati, Domenica Cavone, Maria Celeste Delfino, Luigi De Maria, Antonio Caputi, Giovanni Maria Ferri and Gabriella Serio

Comments on Vimercati et al., 2019, “Asbestos exposure and malignant mesothelioma of the tunica vaginalis testis: a systematic review and the experience of the Apulia (southern Italy) mesothelioma register”

Authors: Gabor Mezei, Ellen T. Chang, Fionna S. Mowat and Suresh H. Moolgavkar

Developmental fluoride neurotoxicity: an updated review

After the discovery of fluoride as a caries-preventing agent in the mid-twentieth century, fluoridation of community water has become a widespread intervention, sometimes hailed as a mainstay of modern public ...

Authors: Philippe Grandjean

Short-term association between ambient temperature and homicide in South Africa: a case-crossover study

Criminology research has traditionally investigated sociodemographic predictors of crime, such as sex, race, age, and socioeconomic status. However, evidence suggests that short-term fluctuations in crime ofte...

Authors: Abigail Gates, Mitchel Klein, Fiorella Acquaotta, Rebecca M. Garland and Noah Scovronick

Correction to: Managing pollution from antibiotics manufacturing: charting actors, incentives and disincentives

Following publication of the original article [1], the author explained that there are multiple errors in the original article

Authors: Niels Nijsingh, Christian Munthe and D. G. Joakim Larsson

Longitudinal follow-up of health effects among workers handling engineered nanomaterials: a panel study

Although no human illness to date is confirmed to be attributed to engineered nanoparticles, occupational epidemiological studies are needed to verify the health effects of nanoparticles. This study used a rep...

Authors: Wei-Te Wu, Lih-Ann Li, Tsui-Chun Tsou, Shu-Li Wang, Hui-Ling Lee, Tung-Sheng Shih and Saou-Hsing Liou

Fluoride exposure and sleep patterns among older adolescents in the United States: a cross-sectional study of NHANES 2015–2016

Fluoride from environmental sources accumulates preferentially in the pineal gland which produces melatonin, the hormone that regulates the sleep-wake cycle. However, the effects of fluoride on sleep regulatio...

Authors: Ashley J. Malin, Sonali Bose, Stefanie A. Busgang, Chris Gennings, Michael Thorpy, Robert O. Wright, Rosalind J. Wright and Manish Arora

Use of skincare products and risk of cancer of the breast and endometrium: a prospective cohort study

Concerns have been raised that extensive use of personal care products that contain endocrine disrupting compounds increase the risk of hormone sensitive cancers.

Authors: Charlotta Rylander, Marit B. Veierød, Elisabete Weiderpass, Eiliv Lund and Torkjel M. Sandanger

Low-moderate arsenic exposure and respiratory in American Indian communities in the Strong Heart Study

Arsenic exposure through drinking water is an established lung carcinogen. Evidence on non-malignant lung outcomes is less conclusive and suggests arsenic is associated with lower lung function. Studies examin...

Authors: Martha Powers, Tiffany R. Sanchez, Maria Grau-Perez, Fawn Yeh, Kevin A. Francesconi, Walter Goessler, Christine M. George, Christopher Heaney, Lyle G. Best, Jason G. Umans, Robert H. Brown and Ana Navas-Acien

The effects of daily meteorological perturbation on pregnancy outcome: follow-up of a cohort of young women undergoing IVF treatment

Human reproduction follows a seasonal pattern with respect to spontaneous conception, a phenomenon wherein the effect of meteorological fluctuations might not be unique. However, the effect of seasonal variati...

Authors: Mingpeng Zhao, Haoyang Zhang, Tarah H. B. Waters, Jacqueline Pui Wah Chung, Tin Chiu Li and David Yiu Leung Chan

Saliva cortisol in relation to aircraft noise exposure: pooled-analysis results from seven European countries

Many studies have demonstrated adverse effects of exposure to aircraft noise on health. Possible biological pathways for these effects include hormonal disturbances. Few studies deal with aircraft noise effect...

Authors: Clémence Baudin, Marie Lefèvre, Jenny Selander, Wolfgang Babisch, Ennio Cadum, Marie-Christine Carlier, Patricia Champelovier, Konstantina Dimakopoulou, Danny Huithuijs, Jacques Lambert, Bernard Laumon, Göran Pershagen, Töres Theorell, Venetia Velonaki, Anna Hansell and Anne-Sophie Evrard

Air pollution and mortality in a large, representative U.S. cohort: multiple-pollutant analyses, and spatial and temporal decompositions

Cohort studies have documented associations between fine particulate matter air pollution (PM_2.5) and mortality risk. However, there remains uncertainty regarding the contribution of co-pollutants and the stabili...

Authors: Jacob S. Lefler, Joshua D. Higbee, Richard T. Burnett, Majid Ezzati, Nathan C. Coleman, Dalton D. Mann, Julian D. Marshall, Matthew Bechle, Yuzhou Wang, Allen L. Robinson and C. Arden Pope III

Transcriptome-wide analysis of changes in the fetal placenta associated with prenatal arsenic exposure in the New Hampshire Birth Cohort Study

Increasing evidence suggests that prenatal exposure to arsenic, even at common environmental levels, adversely affects child health. These adverse effects include impaired fetal growth, which can carry serious...

Authors: Emily F. Winterbottom, Yuguang Ban, Xiaodian Sun, Anthony J. Capobianco, Carmen J. Marsit, Xi Chen, Lily Wang, Margaret R. Karagas and David J. Robbins

Wrangling environmental exposure data: guidance for getting the best information from your laboratory measurements

Environmental health and exposure researchers can improve the quality and interpretation of their chemical measurement data, avoid spurious results, and improve analytical protocols for new chemicals by closel...

Authors: Julia O. Udesky, Robin E. Dodson, Laura J. Perovich and Ruthann A. Rudel

Effect of apparent temperature on daily emergency admissions for mental and behavioral disorders in Yancheng, China: a time-series study

Very few studies have focused on the relationship between ambient apparent temperature (AT) and admission of mental and behaviour disorders (MDs). Therefore, a time-series study was conducted in Yancheng, Chin...

Authors: Min Min, Tingting Shi, Pengpeng Ye, Yuan Wang, Zhenhai Yao, Shun Tian, Yun Zhang, Mingming Liang, Guangbo Qu, Peng Bi, Leilei Duan and Yehuan Sun

Association between prenatal exposure to perfluoroalkyl substances and asthma in 5-year-old children in the Odense Child Cohort

Asthma is the most common non-communicable disease in children. Prenatal exposure to perfluoroalkyl substances (PFASs), a group of persistent environmental chemicals with endocrine disrupting abilities, has be...

Authors: Iben Have Beck, Clara Amalie Gade Timmermann, Flemming Nielsen, Greet Schoeters, Camilla Jøhnk, Henriette Boye Kyhl, Arne Høst and Tina Kold Jensen

Maternal exposure to ambient fine particulate matter and risk of premature rupture of membranes in Wuhan, Central China: a cohort study

The associations between maternal exposure to ambient PM_2.5 during pregnancy and the risk of premature rupture of membranes (PROM) and preterm premature rupture of membranes (PPROM) are controversial. And no rele...

Authors: Kun Wang, Yu Tian, Huabo Zheng, Shengshuai Shan, Xiaofang Zhao and Chengyun Liu

Managing pollution from antibiotics manufacturing: charting actors, incentives and disincentives

Emissions of high concentrations of antibiotics from manufacturing sites select for resistant bacteria and may contribute to the emergence of new forms of resistance in pathogens. Many scientists, industry, po...

Authors: Niels Nijsingh, Christian Munthe and D. G. Joakim Larsson

Determinants of arsenic methylation efficiency and urinary arsenic level in pregnant women in Bangladesh

Prenatal inorganic arsenic (iAs) exposure is associated with pregnancy outcomes. Maternal capabilities of arsenic biotransformation and elimination may influence the susceptibility of arsenic toxicity. Therefo...

Authors: Shangzhi Gao, Pi-I Lin, Golam Mostofa, Quazi Quamruzzaman, Mahmudur Rahman, Mohammad Lutfar Rahman, Li Su, Yu-mei Hsueh, Marc Weisskopf, Brent Coull and David Chistopher Christiani

How can the integrity of occupational and environmental health research be maintained in the presence of conflicting interests?

The sciences, and especially the research subspecialties of occupational and environmental health, are being misused. The misuse serves to interfere with the advancement of policies that depend on rational evi...

Authors: Xaver Baur, Colin L. Soskolne and Lisa A. Bero

Time-varying associations between prenatal metal mixtures and rapid visual processing in children

Humans are exposed to mixtures of chemicals across their lifetimes, a concept sometimes called the “exposome.” Mixtures likely have temporal “critical windows” of susceptibility like single agents and measurin...

Authors: Yuri Levin-Schwartz, Chris Gennings, Lourdes Schnaas, María del Carmen Hernández Chávez, David C. Bellinger, Martha Maria Téllez-Rojo, Andrea A. Baccarelli and Robert O. Wright

Serum dioxin and DNA methylation in the sperm of operation ranch hand veterans exposed to Agent Orange

Exposure to the herbicide Agent Orange during the Vietnam War was widespread and is associated with numerous adverse health outcomes. A continuing concern of veterans is the possibility that exposure to the di...

Authors: Karl T. Kelsey, Matthew Rytel, Edward Dere, Rondi Butler, Melissa Eliot, Susan M. Huse, E. Andres Houseman, Devin C. Koestler and Kim Boekelheide

Does the oxidative stress play a role in the associations between outdoor air pollution and persistent asthma in adults? Findings from the EGEA study

Evidences that oxidative stress plays a role in the associations between outdoor air pollution and asthma are growing. We aimed to study the role of plasma fluorescent oxidation products levels (FlOPs; an oxid...

Authors: Anaïs Havet, Zhen Li, Farid Zerimech, Margaux Sanchez, Valérie Siroux, Nicole Le Moual, Bert Brunekreef, Nino Künzli, Bénédicte Jacquemin, Raphaëlle Varraso, Régis Matran and Rachel Nadif

Morbidity burden of respiratory diseases attributable to ambient temperature: a case study in a subtropical city in China

There are significant associations between ambient temperature and respiratory disease mortality. However, few studies have assessed the morbidity burdens of various respiratory diseases that are attributable ...

Authors: Yiju Zhao, Zhao Huang, Shengyong Wang, Jianxiong Hu, Jianpeng Xiao, Xing Li, Tao Liu, Weilin Zeng, Lingchuan Guo, Qingfeng Du and Wenjun Ma

Methodological limitations in experimental studies on symptom development in individuals with idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF) – a systematic review

Hypersensitivity to electromagnetic fields (EMF) is a controversial condition. While individuals with idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF) claim to experience hea...

Authors: Kristina Schmiedchen, Sarah Driessen and Gunnhild Oftedal

Impact of high drinking water nitrate levels on the endogenous formation of apparent N-nitroso compounds in combination with meat intake in healthy volunteers

Nitrate is converted to nitrite in the human body and subsequently can react with amines and amides in the gastrointestinal tract to form N-nitroso compounds (NOCs), which are known to be carcinogenic in animals....

Authors: Simone G. van Breda, Karen Mathijs, Virág Sági-Kiss, Gunter G. Kuhnle, Ben van der Veer, Rena R. Jones, Rashmi Sinha, Mary H. Ward and Theo M. de Kok

Association of low-level blood lead with serum uric acid in U.S. adolescents: a cross-sectional study

Uncertainty remains regarding the association between blood lead levels (BLL) and serum uric acid (SUA) with relatively low BLL exposure because of limited data in the adolescent population. We examined the as...

Authors: Guiping Hu, Guang Jia, Shichuan Tang, Pai Zheng and Lihua Hu

Prenatal maternal and childhood bisphenol a exposure and brain structure and behavior of young children

Bisphenol A (BPA) is commonly used in the manufacture of plastics and epoxy resins. In North America, over 90% of the population has detectable levels of urinary BPA. Human epidemiological studies have reporte...

Authors: Melody N. Grohs, Jess E. Reynolds, Jiaying Liu, Jonathan W. Martin, Tyler Pollock, Catherine Lebel and Deborah Dewey

Low concentrations of fine particle air pollution and mortality in the Canadian Community Health Survey cohort

Approximately 2.9 million deaths are attributed to ambient fine particle air pollution around the world each year (PM_2.5). In general, cohort studies of mortality and outdoor PM_2.5 concentrations have limited inf...

Authors: Tanya Christidis, Anders C. Erickson, Amanda J. Pappin, Daniel L. Crouse, Lauren L. Pinault, Scott A. Weichenthal, Jeffrey R. Brook, Aaron van Donkelaar, Perry Hystad, Randall V. Martin, Michael Tjepkema, Richard T. Burnett and Michael Brauer

Geomagnetic disturbances driven by solar activity enhance total and cardiovascular mortality risk in 263 U.S. cities

Short-term geomagnetic disturbances (GMD) driven by the quasi-periodic 11-year cycle of solar activity have been linked to a broad range of adverse health effects, including cardiovascular diseases (CVD) and t...

Authors: Carolina Leticia Zilli Vieira, Danilo Alvares, Annelise Blomberg, Joel Schwartz, Brent Coull, Shaodan Huang and Petros Koutrakis

Changes in triggering of ST-elevation myocardial infarction by particulate air pollution in Monroe County, New York over time: a case-crossover study

Previous studies have reported that fine particle (PM_2.5) concentrations triggered ST elevation myocardial infarctions (STEMI). In Rochester, NY, multiple air quality policies and economic changes/influences from...

Authors: Meng Wang, Philip K. Hopke, Mauro Masiol, Sally W. Thurston, Scott Cameron, Frederick Ling, Edwin van Wijngaarden, Daniel Croft, Stefania Squizzato, Kelly Thevenet-Morrison, David Chalupa and David Q. Rich

Association between a urinary biomarker for exposure to PAH and blood level of the acute phase protein serum amyloid A in coke oven workers

Coke oven workers are exposed to both free and particle bound PAH. Through this exposure, the workers may be at increased risk of cardiovascular diseases. Systemic levels of acute phase response proteins have ...

Authors: Niels Hadrup, Danuta Mielżyńska-Švach, Agnieszka Kozłowska, Manuela Campisi, Sofia Pavanello and Ulla Vogel

Association of urinary concentrations of early pregnancy phthalate metabolites and bisphenol A with length of gestation

Environmental exposure to phthalates and bisphenol A (BPA) may have endocrine disrupting effects that alter length of gestation. We assessed the association between the urinary concentrations of 11 phthalate m...

Authors: Helen B. Chin, Anne Marie Jukic, Allen J. Wilcox, Clarice R. Weinberg, Kelly K. Ferguson, Antonia M. Calafat, D. Robert McConnaughey and Donna D. Baird

Making the invisible visible: results of a community-led health survey following PFAS contamination of drinking water in Merrimack, New Hampshire

In March 2016, citizens of Merrimack, New Hampshire, learned that their public water supply was contaminated with perfluorooctanoic acid (PFOA). A subsequent state-led investigation revealed widespread contami...

Authors: Bindu Panikkar, Benjamin Lemmond, Laurene Allen, Carol DiPirro and Shaina Kasper

Asbestos exposure and malignant mesothelioma of the tunica vaginalis testis: a systematic review and the experience of the Apulia (southern Italy) mesothelioma register

Malignant mesothelioma of the tunica vaginalis testis (MMTVT) is a rare disease with a poor prognosis. The diagnosis and management of these lesions are often difficult for pathologists, surgeons, oncologists ...

Authors: Luigi Vimercati, Domenica Cavone, Maria Celeste Delfino, Luigi De Maria, Antonio Caputi, Giovanni Maria Ferri and Gabriella Serio

Ambient air pollution is associated with pediatric pneumonia: a time-stratified case–crossover study in an urban area

Pneumonia, the leading reason underlying childhood deaths, may be triggered or exacerbated by air pollution. To date, only a few studies have examined the association of air pollution with emergency department...

Authors: Chi-Yung Cheng, Shih-Yu Cheng, Chien-Chih Chen, Hsiu-Yung Pan, Kuan-Han Wu and Fu-Jen Cheng

An overview of methods to address distinct research questions on environmental mixtures: an application to persistent organic pollutants and leukocyte telomere length

Numerous methods exist to analyze complex environmental mixtures in health studies. As an illustration of the different uses of mixture methods, we employed methods geared toward distinct research questions co...

Authors: Elizabeth A. Gibson, Yanelli Nunez, Ahlam Abuawad, Ami R. Zota, Stefano Renzetti, Katrina L. Devick, Chris Gennings, Jeff Goldsmith, Brent A. Coull and Marianthi-Anna Kioumourtzoglou

Thyroid hormone levels associate with exposure to polychlorinated biphenyls and polybrominated biphenyls in adults exposed as children

Michigan residents were directly exposed to endocrine-disrupting compounds, polybrominated biphenyl (PBB) and polychlorinated biphenyl (PCB). A growing body of evidence suggests that exposure to certain endocr...

Authors: Sarah W. Curtis, Metrecia L. Terrell, Melanie H. Jacobson, Dawayland O. Cobb, Victoria S. Jiang, Michael F. Neblett, Sabrina A. Gerkowicz, Jessica B. Spencer, M. Elizabeth Marder, Dana Boyd Barr, Karen N. Conneely, Alicia K. Smith and Michele Marcus

Potential role of polycyclic aromatic hydrocarbons as mediators of cardiovascular effects from combustion particles

Air pollution is the most important environmental risk factor for disease and premature death, and exposure to combustion particles from vehicles is a major contributor. Human epidemiological studies combined ...

Authors: Jørn A. Holme, Bendik C. Brinchmann, Magne Refsnes, Marit Låg and Johan Øvrevik

Personal carbon monoxide exposure, respiratory symptoms, and the potentially modifying roles of sex and HIV infection in rural Uganda: a cohort study

Most of the global burden of pollution-related morbidity and mortality is believed to occur in resource-limited settings, where HIV serostatus and sex may influence the relationship between air pollution expos...

Authors: Crystal M. North, Piers MacNaughton, Peggy S. Lai, Jose Vallarino, Samson Okello, Bernard Kakuhikire, Alexander C. Tsai, Marcia C. Castro, Mark J. Siedner, Joseph G. Allen and David C. Christiani

Impact of the warm summer 2015 on emergency hospital admissions in Switzerland

Only a few studies have examined the impact of a particular heat event on morbidity. The aim of this study was to evaluate the impact of the warm summer 2015 on emergency hospital admissions (EHA) in Switzerla...

Authors: Martina S. Ragettli, Ana M. Vicedo-Cabrera, Benjamin Flückiger and Martin Röösli

Long-term exposure to air pollution and hospitalization for dementia in the Rome longitudinal study

Few studies have explored the role of air pollution in neurodegenerative processes, especially various types of dementia. Our aim was to evaluate the association between long-term exposure to air pollution and...

Authors: Francesco Cerza, Matteo Renzi, Claudio Gariazzo, Marina Davoli, Paola Michelozzi, Francesco Forastiere and Giulia Cesaroni

Cumulative asbestos exposure and mortality from asbestos related diseases in a pooled analysis of 21 asbestos cement cohorts in Italy

Despite the available information on cancer risk, asbestos is used in large areas in the world, mostly in the production of asbestos cement. Moreover, questions are raised regarding the shape of the dose respo...

Authors: Ferdinando Luberto, Daniela Ferrante, Stefano Silvestri, Alessia Angelini, Francesco Cuccaro, Anna Maria Nannavecchia, Enrico Oddone, Massimo Vicentini, Francesco Barone-Adesi, Tiziana Cena, Dario Mirabelli, Lucia Mangone, Francesca Roncaglia, Orietta Sala, Simona Menegozzo, Roberta Pirastu…

Acute effects of fine particulate matter (PM_2.5) on hospital admissions for cardiovascular disease in Beijing, China: a time-series study

Air pollution and cardiovascular disease are increasing problems in China. However, the short-term association between fine particulate matter (PM_2.5) and cardiovascular disease (CVD) is not well documented. The ...

Authors: Endawoke Amsalu, Tianqi Wang, Haibin Li, Yue Liu, Anxin Wang, Xiangtong Liu, Lixin Tao, Yanxia Luo, Feng Zhang, Xinghua Yang, Xia Li, Wei Wang and Xiuhua Guo

CYP1A1 methylation mediates the effect of smoking and occupational polycyclic aromatic hydrocarbons co-exposure on oxidative DNA damage among Chinese coke-oven workers

Multiple factors, including co-exposure between lifestyle and environmental risks, are important in susceptibility to oxidative DNA damage. However, the underlying mechanism is not fully understood. This study...

Authors: Yanli Liu, Xuejing Li, Bin Zhang, Ye Fu, Aimin Yang, Hongjie Zhang, Huitao Zhang, Yingying Niu, Jisheng Nie and Jin Yang

Correction to: Exposure to arsenic in utero is associated with various types of DNA damage and micronuclei in newborns: a birth cohort study

Following publication of the original article [1], the author reported that incorrect version of Tables 1, 3, 5 and 6 were published.

Authors: Panida Navasumrit, Krittinee Chaisatra, Jeerawan Promvijit, Varabhorn Parnlob, Somchamai Waraprasit, Chalida Chompoobut, Ta Thi Binh, Doan Ngoc Hai, Nguyen Duy Bao, Nguyen Khac Hai, Kyoung-Woong Kim, Leona D. Samson, Joseph H. Graziano, Chulabhorn Mahidol and Mathuros Ruchirawat

Neurocognitive impact of metal exposure and social stressors among schoolchildren in Taranto, Italy

Metal exposure is a public health hazard due to neurocognitive effects starting in early life. Poor socio-economic status, adverse home and family environment can enhance the neurodevelopmental toxicity due to...

Authors: Roberto G. Lucchini, Stefano Guazzetti, Stefano Renzetti, Michele Conversano, Giuseppa Cagna, Chiara Fedrighi, Augusto Giorgino, Marco Peli, Donatella Placidi, Silvia Zoni, Giovanni Forte, Costanza Majorani, Anna Pino, Oreste Senofonte, Francesco Petrucci and Alessandro Alimonti

Susceptibility of prediabetes to the health effect of air pollution: a community-based panel study with a nested case-control design

Recent studies suggest that people with diabetes or who are at risk of developing diabetes, i.e. prediabetic (preDM), are potentially susceptible to air pollution, but the underlying mechanisms remain unclear ...

Authors: Yiqun Han, Yanwen Wang, Weiju Li, Xi Chen, Tao Xue, Wu Chen, Yunfei Fan, Xinghua Qiu and Tong Zhu